Thimble microscope system

Kamal, Tahseen; Rubinstein, Jaden; Watkins, Rachel; Cen, Zijian; Kong, Gary; Lee, Woei Ming

doi:10.1117/12.2242949

Cited by 1 publication

(2 citation statements)

References 7 publications

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“…[22][23][24][25] To fabricate this elastomeric lens, the droplet-based fabrication techniques are especially popular as they offer a simple and fast fabrication process. [25,[32][33][34][35][36] In the injection method, the liquid PDMS is injected on top of a substrate and cured with a heating treatment. Currently, there are two popular ways to fabricate the lens with PDMS droplet on a substrate including the upright injection [26][27][28][29][30][31] and hanging method.…”

Section: Pdms Lens Fabricationmentioning

confidence: 99%

See 1 more Smart Citation

Portable Smartphone‐Based Platform for Real‐Time Particle Detection in Microfluidics

Salafi

Zeming

Lim

et al. 2018

Adv Materials Technologies

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Real‐time particle detection is an integral part of microfluidics for diagnostics. The detection method is typically performed with the use of bulky and expensive instruments including a bench‐top microscope, high‐speed camera, and fluidic pump. This limits the practical applications of microfluidics for real‐time point‐of‐care detection. Here, a portable and low‐cost smartphone microscopy platform is developed for real‐time particle detection in microfluidics based on a polydimethylsiloxane (PDMS) lens, modular 3D printed accessory, plug‐and‐play paper pump, and a novel particle counting algorithm. The PDMS lens is developed using a new method based on the PDMS precuring and hydrophobic modification on a pillar template to allow for fabrication of various lens shapes with high reproducibility and broad range magnification ratio from 30× to 100×. The modular 3D printed smartphone accessory allows for easy imaging setup to cater for different size of microchannel and the paper pump design provides a convenient single‐step process to drive the fluid. The platform is implemented to count the moving particles in the outlet of microfluidics deterministic lateral displacement with 94% counting accuracy. This platform provides huge potential applications for real‐time point‐of‐care detection that can be integrated with various microfluidic techniques.

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Section: Pdms Lens Fabricationmentioning

confidence: 99%

“…The lens magnification can be approximated by M = 250/f, where f is the focal length (in mm) that can be obtained using the lensmaker's formula [20,33] ( ) The untreated liquid PDMS drop spread well over a glass surface, resulting in a flat droplet with a low contact angle.…”

Section: Substrate Hydrophobicity and Pdms Precuringmentioning

confidence: 99%