Thiocyanate Ion Selective Solid Contact Electrode Based on Mn Complex of N,N'-BIs-(4-Phenylazosalicylidene)-O-Phenylene Diamine Ionophore

Han, Won‐Sik; Hong, Tae‐Kee; Lee, Younghoon

doi:10.4236/ajac.2011.26084

Cited by 9 publications

(2 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some other macrocyclic compounds such as aza-macrocycles [41][42][43], crown ethers [44] or calix [4]arenes [45] were also reported. The second most exploited systems are organic and metalloorganic non-macrocyclic complexes [46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62]. All presented ionophores are characterized by good selectivity over chlorides, but the low selectivity over two other ions present at high levels in human saliva, namely HCO 3 − and H 2 PO 4 − .…”

Section: Introductionmentioning

confidence: 99%

Potentiometric Solid-Contact Ion-Selective Electrode for Determination of Thiocyanate in Human Saliva

Urbanowicz

Sadowska

Pijanowska

et al. 2020

Sensors

View full text Add to dashboard Cite

A new solid-contact potentiometric ion-selective electrode for the determination of SCN− (SCN-ISE) has been described. Synthesized phosphonium derivative of calix[4]arene was used as a charged ionophore. The research included selection of the ion-selective membrane composition, determination of the ISEs metrological parameters and SCN-ISE application for thiocyanate determination in human saliva. Preparation of the ISEs included selection of a plasticizer for the ion-selective membrane composition and type of the electrode material. The study was carried out using ISE with liquid internal electrolyte (LE-ISE) and solid-contact electrodes made of glassy carbon (GC-ISE) and gold rods (Au-ISE). The best parameters were found for GC sensors for which the ion-selective membrane contained chloroparaffin as a plasticizer (S = 59.9 mV/dec, LOD = 1.6 × 10−6 M). The study of potentiometric selectivity coefficients has shown that the thiocyanate-selective sensor could be applied in biomedical research for determination of SCN− concentration in human saliva. The accuracy of the SCN− determination was verified by testing 59 samples of volunteers’ saliva by potentiometric sensors and UV-Vis spectrophotometry as a reference technique. Moreover, SCN− concentrations in the smokers’ and non-smokers’ saliva were compared. In order to investigate the influence of various factors (sex, health status, taken medications) on the thiocyanate level in the saliva, more extensive studies on a group of 100 volunteers were carried out. Additionally, for a group of 18 volunteers, individual profiles of SCN− concentration in saliva measured on a daily basis for over a month were collected.

show abstract

Section: Introductionmentioning

confidence: 99%

Potentiometric Solid-Contact Ion-Selective Electrode for Determination of Thiocyanate in Human Saliva

Urbanowicz

Sadowska

Pijanowska

et al. 2020

Sensors

View full text Add to dashboard Cite

show abstract

“…Many ionophores have been used for thiocyanate monitoring using solid contact potentiometric electrodes. [27][28][29][30][31][32] Although these sensors exhibit an anti-Hoffmeister selectivity order, they suffer from strong interference by I -, CN -, NO 2 -, IO 4 -, ClO 4 -, Br -, and N 3 -. In addition, some of these sensors suffer from the disadvantages of limited range of the linear response, and a long response time.…”

Section: Introductionmentioning

confidence: 99%

Potentiometric Study for Rapid Continuous Monitoring of Trace Level Thiocyanate Using Solid and Conventional Types PVC Membrane Sensors

Kamel

2018

ECB

View full text Add to dashboard Cite

A comparative study using two different thiocyanate electrode designs was conducted; a solid type electrode (type A) and conventional liquid inner contact electrode (type B). The fabrication of these electrodes was based on Al (III) [4-(2-Pyridylazo) resorcinol] (Al/PAR) and Mg (II) phthalocyanine (MgPC) complexes as a charged carrier, aliquate 336S and TDMAC as ion exchangers in plasticized poly (vinyl chloride) membrane. Electrodes type (A) revealed significantly enhanced response towards SCNions with displayed near-Nernstian slope of-53.7-55.8 mV decade-1 over the concentration range 5.0x10-6-1.0x10-2 mol L-1 and a detection limit of 0.4-3.7 µg mL-1. Type (B) sensors revealed near-Nernstian potential response to SCNwith a slope of-45.9-62.4 mV decade-1 over a linear range of 5.0x10-5-1.0x10-2 mol L-1 and a detection limit of 0.12-0.3 µg mL-1. Membrane sensors based on (Al/PAR) and (MgPC) using the so called "fixed interference method" (FIM) exhibited a good selectivity over different anions which differ significantly from the classical Hofmeister series. All sensors were integrated in a flow system for continuous monitoring of thiocyanate under hydrodynamic mode of operation. The sensors revealed a frequency of ~ 54 samples h-1. Application of the proposed sensors for SCNdetermination in biological fluid samples such as saliva collected from some non-smoker and smoker donors. Determination of cyanide content in electroplating wastewater samples after its conversion into thiocyanate was also applied. The results obtained from the proposed sensors were agreed with that obtained using the standard methods of thiocyanate and cyanide analysis.

show abstract

Potentiometric Anion Selectivity and Analytical Applications of Polymer Membrane Electrodes Based on Novel Mn(III)‐ and Mn(IV)‐Salophen Complexes

2016

View full text Add to dashboard Cite

New Mn(III)‐L and Mn(IV)‐L complexes were prepared from the highly lipophilic salophen ligand (L): phenol 2,2′‐[(4,5‐dimethyl‐1,2‐phenylene)bis[(E)‐nitrilomethylidyne]]bis[4,6‐bis(1,1‐dimethylethyl). The prepared complexes were fully characterized and used for the construction of thiocyanate membrane electrodes. Optimized membrane electrodes contained 33.0 mg PVC, 66.0 mg o‐nitrophenyloctylether, 50 or 5 (mole %) tetrakis(trifluoromethyl)phenyl borate and 1 mg Mn(III)‐L (sensor 2) or Mn‐(IV)‐L (sensor 12), respectively. Such electrodes exhibited linear responses toward thiocynate in a concentration range of 10−1–10−5 M and detection limits of 8.3×10−6, 8.9×10−6 M for sensor 2 and 12, respectively. Optimized membrane electrodes exhbited high selectivty toward thiocayante compared to more lipophilic anions. The observed thiocyanate selectivity of the optimized membranes was confirmed by formation constant calculations for Mn(III)‐L and Mn(IV)‐L with SCN−, β=1014.1 and 1012.5, which was measured potentiometrically using the sandwich membrane method. Furthermore, computational study using DFT calculations was performed to at DFT/B3LYP level of theory to confirm the observed selectivity data. The response times were 3 and 0.5 min for low and high concentrations. The lifetimes of the optimized electrodes were ∼4–6 weeks. The analytical utility of the optimized membrane electrodes was demonstrated by the analysis of thiocyanate level in different saliva samples.

show abstract

Thiocyanate Ion Selective Solid Contact Electrode Based on Mn Complex of N,N'-BIs-(4-Phenylazosalicylidene)-O-Phenylene Diamine Ionophore

Cited by 9 publications

References 76 publications

Potentiometric Solid-Contact Ion-Selective Electrode for Determination of Thiocyanate in Human Saliva

Potentiometric Solid-Contact Ion-Selective Electrode for Determination of Thiocyanate in Human Saliva

Potentiometric Study for Rapid Continuous Monitoring of Trace Level Thiocyanate Using Solid and Conventional Types PVC Membrane Sensors

Potentiometric Anion Selectivity and Analytical Applications of Polymer Membrane Electrodes Based on Novel Mn(III)‐ and Mn(IV)‐Salophen Complexes

Contact Info

Product

Resources

About