Thiourea Therapy and Blood Cholesterol

Pharmacology

“…introduced into the duodenum has a moderate diuretic action, but has no effect on blood pressure and respiration (212). Therapeutic doses of thiourea in man cause a rise of blood cholesterol (219). Large doses in adult rats, given repeatedly by mouth or intra peritoneally, in addition to effecting thyroid enlargement and a fall of metabolic rate, are followed by fatal pulmonary edema (220).…”