Third-degree atrioventricular block in an adolescent following acute alcohol intoxication

Cleef, Anne N. H. van; Schuurman, Marijn J; Busari, Jamiu O

doi:10.1136/bcr.07.2011.4547

Cited by 8 publications

(3 citation statements)

References 18 publications

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“…The P wave is also prolonged in moderate to severe, acute ethanol intoxication (9). The significance of this observation is supported by anecdotal evidence of third degree atrioventricular blockade following acute ethanol intoxication (10,11).…”

Section: Functional Heart Disease and Ethanol Consumptionmentioning

confidence: 79%

Alcohol and Heart Disease in the Forensic Setting

Cunningham

2014

Academic Forensic Pathology

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The impacts of chronic high levels of ethanol consumption on cardiovascular structure and function are reviewed as they pertain to forensic pathology practice. Both hypertrophy and remodeling of the myocardium as well as physiological revision of electrical conduction through the heart can occur in a progressive fashion. A discussion about the likely underappreciated spectrum of structural heart disease that may be seen in individuals with chronic alcohol dependence is presented. Finally, brief reference to the collision between alcohol, cardiovascular disease, and forensically relevant scenarios is provided.

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Section: Functional Heart Disease and Ethanol Consumptionmentioning

confidence: 79%

Alcohol and Heart Disease in the Forensic Setting

Cunningham

2014

Academic Forensic Pathology

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“…Interestingly, previous case reports have described AV blocks of varying degrees occurring after binge drinking episodes. 14 , 15 Small historic experimental reports in the setting of acute alcohol ingestion have also demonstrated prolongation of sinus node recovery, His-ventricular intervals, and QRS duration, 16 , 17 though in contrast, one study demonstrated improvements in AV conduction. 18 More recently, data from a large population of mostly young and healthy attendants of the 2015 Munich Octoberfest, who undertook one-lead electrocardiogram (ECG) recordings and handheld breath alcohol measurement, did not demonstrate a significant association between blood alcohol concentration and PR interval, QRS duration, and QTc interval, though blood alcohol concentration was associated with an increase in heart rate.…”

Section: Discussionmentioning

confidence: 99%

Alcohol intake and bradyarrhythmia risk: a cohort study of 407 948 individuals

Gallagher

Elliott

et al. 2022

EP Europace

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Aims There is a paucity of epidemiological evidence on alcohol and the risk of bradyarrhythmias. We thus characterized associations of total and beverage-specific alcohol consumption with incident bradyarrhythmias using data from the UK Biobank. Methods and results Alcohol consumption reported at baseline was calculated as UK standard drinks (8 g alcohol)/week. Bradyarrhythmia events were defined as sinus node dysfunction (SND), high-level atrioventricular block (AVB), and permanent pacemaker implantations. Outcomes were assessed through hospitalization and death records, and dose–response associations were characterized using Cox regression models with correction for regression dilution bias. We studied 407 948 middle-aged individuals (52.4% female). Over a median follow-up time of 11.5 years, a total of 8 344 incident bradyarrhythmia events occurred. Increasing total alcohol consumption was not associated with an increased risk of bradyarrhythmias. Beer and cider intake were associated with increased bradyarrhythmia risk up to 12 drinks/week; however, no significant associations were observed with red wine, white wine, or spirit intake. When bradyarrhythmia outcomes were analysed separately, a negative curvilinear was observed for total alcohol consumption and risk of SND, but no clear association with AVB was observed. Conclusion In this predominantly White British cohort, increasing total alcohol consumption was not associated with an increased risk of bradyarrhythmias. Associations appeared to vary according to the type of alcoholic beverage and between different types of bradyarrhythmias. Further epidemiological and experimental studies are required to clarify these findings.

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“…Interestingly, previous case reports have described AV blocks of varying degrees occurring after binge drinking episodes. 14,15 Small historic experimental reports in the setting of acute alcohol ingestion have also demonstrated prolongation of sinus node recovery, Hisventricular intervals, and QRS duration, 16,17 though in contrast, one study demonstrated improvements in AV conduction. 18 More recently, data from a large population of mostly young and healthy attendants of the 2015 Munich Octoberfest, who undertook onelead electrocardiogram (ECG) recordings and handheld breath alcohol measurement, did not demonstrate a significant association between blood alcohol concentration and PR interval, QRS duration, and QTc interval, though blood alcohol concentration was associated with an increase in heart rate.…”

Section: Discussionmentioning

confidence: 99%