Thirty-Day Mortality Rate of Patients With Hip Fractures During the COVID-19 Pandemic: A Single Centre Prospective Study in the United Kingdom

Abstract

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Thirty-day mortality of patients with hip fracture during COVID-19 pandemic and pre-pandemic periods: A systematic review and meta-analysis

“…A total of 45 studies were retrieved after the search of electronic databases using the keywords; of which, eight studies were eligible for review after screening[ 9 , 19 , 20 , 27 - 29 , 38 , 39 ] (Figure 1 ). There were three prospective studies and five retrospective comparative studies.…”

“…Pooled analysis of 30-d mortality from the eight studies ( n = 1586) revealed a significantly increased death among hip fracture patients during the pandemic time (9.63% vs 6.33%; OR, 0.62; 95%CI, 0.33, 1.17; P = 0.14) (Table 3 , Figure 3 )[ 9 , 19 , 20 , 27 - 29 , 38 , 39 ]. There was no difference in 30-d mortality rate between COVID-19 negative patients who were treated during the pandemic time and all hip fractured patients treated during the pre-pandemic period (6.44% vs 5.74%; OR, 1.03; 95%CI, 0.61, 1.75; P = 0.91)[ 9 , 19 , 20 , 29 , 38 ]. However, a significant difference in mortality rate was observed between COVID-19 + and COVID-19 − patients with an OR of 6.99 (29.33% vs 5.73%; 95%CI, 3.45, 14.16; P < 0.00001) (Table 3 , Figure 3 )[ 9 , 19 , 20 , 29 , 38 ].…”

“…There was no difference in 30-d mortality rate between COVID-19 negative patients who were treated during the pandemic time and all hip fractured patients treated during the pre-pandemic period (6.44% vs 5.74%; OR, 1.03; 95%CI, 0.61, 1.75; P = 0.91)[ 9 , 19 , 20 , 29 , 38 ]. However, a significant difference in mortality rate was observed between COVID-19 + and COVID-19 − patients with an OR of 6.99 (29.33% vs 5.73%; 95%CI, 3.45, 14.16; P < 0.00001) (Table 3 , Figure 3 )[ 9 , 19 , 20 , 29 , 38 ].…”

Epidemiological pattern of orthopaedic fracture during the COVID-19 pandemic: A systematic review and meta-analysis

“…For example, surgery performed within 24 h of admission to patients with a hip fracture significantly reduces 1-year mortality and morbidity, while delaying surgery may increase the likelihood of 30-day mortality and complications. 34 , 36 This meta-analysis noted an increase in mortality in patients with fracture during the pandemic. Although the specific cause was not reported, the abovementioned factors are thought to have contributed to the higher proportion of deaths.…”

The Many Faces of Covid-19 at a Glance: A University Hospital Multidisciplinary Account From Milan, Italy

“…Of major concern 30-day mortality among hip fracture patients during the first 30 days of the pandemic increased. A positive Covid-19 test in patients with hip fractures is associated with a 2.4-fold increase in the risk of 30-day mortality (65).…”