Thirty‐Five‐Day Modified Red Cells and 7‐Day Stored Platelet Concentrates from Triple Bags of Identical PVC Formulation

Lovric, V.A.; Archer, G. T. L.; Wisdom, L.; Robson, June; Raftos, Julia E.; Coulits, Nelly; Ribeiro, A.; Stewart, Michael H.; Jindra, J; Schüller, M.

doi:10.1111/j.1423-0410.1985.tb00791.x

Cited by 22 publications

(13 citation statements)

References 6 publications

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“…When blood is cross-matched for surgery, it is unavailable for others for 24 to 48 hours, and the chance 13 which can be extended to 42 days when AS-1 (Adsol) or AS-3 (Nutricel) is used. 14,15 This duration has been set by federal regulation and is determined by the requirement that Ն75% of the transfused cells remain in circulation after infusion. However, evidence suggests that the oxygen delivery capacity of the RBCs decreases with time in storage and that patients fare worse after receiving blood stored for increasing lengths of time.…”

Section: Discussionmentioning

confidence: 99%

Blood Use in Cerebrovascular Neurosurgery

Couture

Ellegala

Dumont

et al. 2002

Stroke

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Background and Purpose-This study reviews the perioperative use of red blood cell transfusion in cerebrovascular neurosurgery. The current algorithm for preoperative ordering of red cells is historical and dated. More blood is ordered than is actually transfused, and considerable variability exists between different institutions. We determine the use of blood transfusion in cerebrovascular surgery to develop a rational blood ordering practice. Methods-Records of 301 patients undergoing cerebrovascular neurosurgery at the University of Virginia were reviewed to quantitatively evaluate red blood cell transfusion practices. The amount and reason for transfusion were noted in each case. Results-In 126 patients undergoing carotid endarterectomy, there were no preoperative or intraoperative transfusions and 5 postoperative transfusions (4.0%). In 71 ruptured aneurysm patients, there were 2 preoperative blood transfusions (2.8%), 4 intraoperative transfusions (5.6%), and 15 postoperative transfusions (21.1%). Forty-seven patients underwent surgery for unruptured aneurysms, with no preoperative transfusions, 2 intraoperative transfusions (4.3%), and 8 postoperative blood transfusions (17.0%). Of the 54 patients undergoing surgery for arteriovenous malformations, 5 patients (9.3%) were transfused preoperatively, 4 were transfused intraoperatively (7.4%), and 22 were transfused postoperatively (40.7%). None of the 3 patients undergoing surgery for concomitant arteriovenous malformations and aneurysms received intraoperative blood transfusions, but 1 received blood both preoperatively and postoperatively, and another received a transfusion postoperatively only. The overall ratio of perioperative cross-match to transfusion in this series is 41.4. Conclusions-In vascular neurosurgery at our institution, blood has routinely been ordered excessively. We recommend an ABO-Rh type and antibody screen for aneurysm and arteriovenous malformation surgery and no screen for carotid endarterectomy to efficiently utilize transfusion therapy in cerebrovascular surgery.

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Section: Discussionmentioning

confidence: 99%

Blood Use in Cerebrovascular Neurosurgery

Couture

Ellegala

Dumont

et al. 2002

Stroke

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“…We were then able to issue both modified PRC with a long shelf life and platelet concentrates with a shelf life of 7 days [4], Since the introduction of the circle pack into clinical blood transfusion practice in NSW, Australia, in 1976, there has been a preferential change to the use of the modified PRC in most centres. Many large hospitals now use these modified PRC exclusively (except for exchange transfusion), relying on supplementation with other plas ma and cellular components, when required.…”

Section: Dr Va Lovricmentioning

confidence: 99%

Modified Packed Red Cells and the Development of the Circle Pack

Lovric¹

1986

Vox Sanguinis

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“…Platelets were stored in CLX MKII bags [11] and were suspended in 60 ml of autologous plasma or a synthetic medium composed of acetate, gluconate and chloride, buf fered with bicarbonate [12], In some studies comparing the effects of…”

Section: Preparation Of Blood Componentsmentioning

confidence: 99%

“…Red cells were supended in 100 ml of additive solution. The A AS solution was the one provided in the Tuta bag system [11] and was composed of 2 mM citric acid. 20mMtrisodium citrate.…”

Section: Preparation Of Blood Componentsmentioning

confidence: 99%

“…In standard blood collection 450 mlofbloodwastakeninto63 ml of anticoagulant. The blood bag system used was the triple circle-pack configuration [11] provided by Tuta Laboratories (Lane Cove, NSW. Australia), in which the primary bag is composed of polyvinyl chlo ride plasticised with a mixture of diethylhexyl phthalate and triethyl hexyl trimellitate-CLX Mark II.…”

Section: Blood Collectionmentioning

confidence: 99%

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Red Cell and Platelet Concentrates from Blood Collected into Half- Strength Citrate Anticoagulant: Improved Maintenance of Red Cell 2,3-Diphosphoglycerate in Half-Citrate Red Cells

Farrugia¹,

Douglas²,

James³

et al. 1992

Vox Sanguinis

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This study confirms previous work suggesting equivalent in vitro properties in blood components prepared from donations collected into half-citrate preservative (HCPD) compared to components derived from donations collected into standard citrate-phosphate-dextrose (CPD) preservatives. In addition, red cell products harvested from HCPD donations showed significantly improved maintenance of pH over storage, and this was reflected in improved maintenance of intracellular 2,3-diphosphoglycerate (2,3-DPG). This effect was observed in whole blood and in red cells suspended in a phosphate-containing additive solution (Tuta AAS). Collection into HCPD also improved 2,3-DPG maintenance in red cell concentrates processed following an 18-hour hold at 22 °C. These improvements were less pronounced in red cells suspended in a non-phosphate-containing medium (Fenwal Adsol) in which a higher pH was maintained even in units collected in CPD. Platelets harvested from HCPD blood and suspended in plasma showed equivalent quality to platelets from standard donations. Some deterioration of platelet properties was observed when HCPD platelets were stored in a non-citrate synthetic medium. Together with data indicating improved coagulation factor stability, these results suggest that collection into HCPD improves stored blood quality and may also allow logistical benefits in blood component preparation.

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Thirty‐Five‐Day Modified Red Cells and 7‐Day Stored Platelet Concentrates from Triple Bags of Identical PVC Formulation

Cited by 22 publications

References 6 publications

Blood Use in Cerebrovascular Neurosurgery

Blood Use in Cerebrovascular Neurosurgery

Modified Packed Red Cells and the Development of the Circle Pack

Red Cell and Platelet Concentrates from Blood Collected into Half- Strength Citrate Anticoagulant: Improved Maintenance of Red Cell 2,3-Diphosphoglycerate in Half-Citrate Red Cells

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