“…TUS has demonstrated reasonable sensitivity and high specificity for distinguishing malignant from benign effusions. 48 , 49 Certain specific ultrasound characteristics have been associated with malignancy, such as pleural/diaphragmatic nodules, pleural thickening >1 cm, diaphragmatic thickening >7 mm, visceral pleural thickening, liver metastasis, and the absence of lung air bronchogram signs. 48 , 50 The best predictors of malignancy are pleural or diaphragmatic nodularity ( Fig.…”