“…Although open surgical repair remains the gold standard for treatment of thoracoabdominal aortic aneurysms (TAAA), it still carries significant mortality and serious adverse events, justifying efforts to protect the spinal cord and the visceral organs from ischemia-related complications. Lopez-Marco and colleagues 1 report a very interesting step-by-step illustration of their current approach to open extent II TAAA repair. The authors routinely use sequential aortic crossclamping under left heart bypass with mild passive hypothermia (34°C), selective visceral and medullar isothermic blood perfusion, as well as renal protection through intermittent administration of cold Custodiol solution (Essential Pharmaceuticals, LLC, Durham, NC) in the renal arteries, cerebrospinal fluid drainage, monitoring of motor evoked potentials, and near-infrared spectrometry of cerebral, paraspinal, and lower limbs oxygen saturations.…”