Thoracolumbar disc disease

Sharp, Nancy; Wheeler, S. J.

doi:10.1016/b978-0-7234-3209-8.50012-1

Cited by 67 publications

(81 citation statements)

References 58 publications

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“…The degree of neurologic impairment was graded as 2 of 5 on the scale of Sharp and Wheeler. 1 The primary differential diagnoses included herniation of a degenerated intervertebral disk or vascular myelopathy resulting in spinal cord infarction or hemorrhage. Inflammatory and neoplastic diseases were considered less likely on the basis of the history and signalment of the dog.…”

mentioning

confidence: 99%

Spontaneous regression of lumbar Hansen type 1 disk extrusion detected with magnetic resonance imaging in a dog

Steffen

Kircher

Dennler

2014

javma

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mentioning

confidence: 99%

Spontaneous regression of lumbar Hansen type 1 disk extrusion detected with magnetic resonance imaging in a dog

Steffen

Kircher

Dennler

2014

javma

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“…Thoracolumbar intervertebral disc disease (IVDD) is a common cause of hind limb paresis and paralysis in dogs 1 . Treatment protocols vary from conservative treatment to decompressive surgery 1,2 . Laminectomy followed by meticulous removal of the herniated disc is the treatment of choice for nonambulatory dogs 2 .…”

mentioning

confidence: 99%

Association of Cerebrospinal Fluid Analysis Findings with Clinical Signs and Outcome in Acute Nonambulatory Thoracolumbar Disc Disease in Dogs

Srugo¹,

Aroch²,

Christopher³

et al. 2011

Veterinary Internal Medicne

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Background: Cerebrospinal fluid (CSF) pleocytosis recently was associated with the severity of neurologic signs in dogs with intervertebral disc disease (IVDD).Hypothesis/Objectives: To look for an association among CSF cell counts, total protein concentration, and severity of neurologic signs at presentation with outcome in dogs with acute thoracolumbar IVDD. Our hypothesis was that CSF total nucleated cell count (TNCC) and percentage cell types would be associated with the severity of spinal cord damage and therefore with both the presenting clinical signs and the prognosis of affected dogs.Animals: Fifty-four dogs with acute nonambulatory thoracolumbar IVDD were evaluated. Methods: Retrospective study. Signalment, neurologic grade, CSF TNCC, protein concentration, red blood cells count and differential cell percentages, and short-and long-term outcomes were evaluated.Results: CSF pleocytosis ( 45 cells/mL) was present in 54% of dogs and was positively associated with neurologic grade at presentation and with postoperative time to regaining ambulation. Neutrophils were observed most frequently. The percentage of CSF macrophages and macrophage to monocyte ratio were higher (P 5 .001, for both) in dogs presented without deep pain sensation (DPS) that did not regain ambulation. Receiver operator characteristics curve analysis yielded a cut-off point of 13% macrophages with a sensitivity and specificity of 100 and 83%, respectively, for prediction of a negative outcome.Conclusions and Clinical Importance: CSF pleocytosis is positively associated with the severity of spinal cord damage in dogs with thoracolumbar IVDD. The percentage of CSF macrophages can be used as a prognostic indicator for regaining ambulation in dogs that have lost DPS.

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“…Recently, an FFG twice the size of the defect has been recommended as the appropriate size for hemilaminectomy [10]. However, this recommendation is based on a past report concerning dorsal laminectomy [12].…”

Section: Discussionmentioning

confidence: 89%

“…The aim of laminectomy is to extract the herniated intervertebral disc material from the defect by the excision of a part of the vertebral arch [10]. However, it has been reported that there is a possibility of fibrosis around the defect and adhesion between the exposed dura mater and surrounding tissue [7].…”

mentioning

confidence: 99%

Effect of an Autogenous Free Fat Graft on Hemilaminectomy Defects in Dogs

Shimizu

Koga

Kishimoto

et al. 2009

The Journal of Veterinary Medical Science

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ABSTRACT. The purpose of this study was to evaluate the effect of an autogenous free fat graft (FFG) on hemilaminectomy defects. Hemilaminectomy was performed at three levels in three beagles, and each defect was designated as a control site or a site treated with one of two different sizes of FFG. Subsequently, longitudinal computed tomography scanning and histopathological examination were performed. As a result, no postoperative dural adhesion was recognized at the sites where FFGs were placed regardless of the size of the FFG. Moreover, there was no compression of the spinal cord by the FFG. Therefore, it appears that postoperative dural adhesion was controlled by the FFG and that the possibility of FFG migration into the spinal canal is low in hemilaminectomy. In conclusion, placement of an FFG over the defect was considered useful for preventing complications in hemilaminectomy.

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Thoracolumbar disc disease

Cited by 67 publications

References 58 publications

Spontaneous regression of lumbar Hansen type 1 disk extrusion detected with magnetic resonance imaging in a dog

Spontaneous regression of lumbar Hansen type 1 disk extrusion detected with magnetic resonance imaging in a dog

Association of Cerebrospinal Fluid Analysis Findings with Clinical Signs and Outcome in Acute Nonambulatory Thoracolumbar Disc Disease in Dogs

Effect of an Autogenous Free Fat Graft on Hemilaminectomy Defects in Dogs

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