Thoracoscopic Esophagectomy for a Huge Leiomyosarcoma

Manipadam, John Mathew; Bains, Satinder Pal Singh; Mahesh, Shefali; Emmanuel, Ami Maria; Ramesh, H.

doi:10.1055/s-0039-1696729

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…Mortality associated with surgery for leiomyosarcoma of the esophagus may be due to pulmonary and anastomotic complications. Approaching esophageal leiomyosarcomas by minimally invasive techniques minimize the complications despite of larger tumor size 19 .…”

Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma of stomach extending to gastroesophageal junction and distal esophagus as a rare cause of dysphagia -A case report

Rajthala,

Gyawali,

Banmala

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction and Importance: Gastric leiomyosarcoma is a rare malignant tumor among the primary gastric carcinomas. Among the different common presentations, dysphagia is an uncommon presentation of gastric leiomyosarcoma. Case Presentation: A 29-year-old female presented with complaints of progressive dysphagia for one year associated with vomiting, significant weight loss, and anorexia for six months. On blood investigations, she had anemia, hypokalemia, pre-renal acute kidney injury, and unconjugated hyperbilirubinemia. Upper gastrointestinal endoscopy and contrast-enhanced computed tomography (CECT) were initially suggestive of carcinoma of stomach. Immunohistochemistry was diagnostic of leiomyosarcoma of stomach extending to the gastroesophageal junction and distal esophagus. She underwent total gastrectomy with distal esophagectomy with lateral segmentectomy of liver (non-anatomical) with Roux-en-Y esophago-jejunal anastomosis (end-to-side and retro-colic)) through thoracoabdominal approach. After six weeks, she received four cycles of doxorubicin therapy. Follow-up at 18 months after surgery revealed no recurrence of malignancy. Clinical discussion: Leiomyosarcoma, a rare malignant tumor arising from stomach involves commonly gastric body followed by antrum and fundus. Imaging including CECT and tissue diagnosis including immunohistochemistry [positive for α-SMA, desmin, calponin, h-caldesmon, or smoothelin] have been mainstay for definitive diagnosis. The standard treatment for leiomyosarcoma of stomach is complete surgical resection of tumor because it has malignant potential and does not respond to targeted treatment with a tyrosine kinase inhibitor. The type of surgery depends on the size and localization of the tumor. Conclusions: Early diagnosis with proper imaging, immunohistochemistry, and biopsy play important role in differentiating gastric leiomyosarcoma from GIST. Surgical resection is the mainstay of treatment.

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Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma of stomach extending to gastroesophageal junction and distal esophagus as a rare cause of dysphagia -A case report

Rajthala,

Gyawali,

Banmala

et al. 2024

Annals of Medicine &Amp; Surgery

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“…Background: Leiomyosarcoma is the most common human sarcoma, and oesophageal location is rare, with oesophageal leiomyosarcoma (OLMS) accounting for less than 1% of oesophageal malignancies; nonetheless, leiomyosarcoma is the most common primitive oesophageal sarcoma[ 137 - 139 ].…”

Section: Rare Primitive Oesophageal Malignant Tumours Of Non-epithelimentioning

confidence: 99%

Histopathological landscape of rare oesophageal neoplasms

Businello

Pozzo

Sbaraglia

et al. 2020

WJG

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The landscape of neoplastic pathology of the oesophagus is dominated by malignancies of epithelial origin, in particular by oesophageal adenocarcinoma and oesophageal squamous cell carcinoma. However, several other histopathological variants can be distinguished, some associated with peculiar histopathological profiles and prognostic behaviours and frequently underrecognized in clinical practice. The aim of this review is to provide a comprehensive characterization of the main morphological and clinical features of these rare variants of oesophageal neoplastic lesions.

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“…4) Afterward, surgical resection has become the main treatment for ELS and most of the resections were esophagectomy with reconstruction of the continuity of the digestive tract with the stomach, similar to the resection of the esophageal carcinoma. 2,3,5) We report here a case of enucleation of leiomyosarcoma of cervical esophagus and reconstruction of the defect of the esophagus with sternohyoid muscle.…”

Section: Introductionmentioning

confidence: 99%

Reconstruction of the Esophagus with Sternohyoid Flap after Resection of a Large Cervical Esophageal Leiomyosarcoma

Wei

Tian

et al. 2023

ATCS

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Purpose: Reconstruction of the esophagus with sternohyoid muscle after enucleation of the cervical esophageal leiomyosarcoma (ELS) was rarely reported. Methods: A case of 55-year-old female with a large leiomyosarcoma in the cervical esophagus was reported. The tumor was enucleated, and the defect of the esophagus was patched with left sternohyoid muscle flap. Results: The patient recovered uneventfully after surgery. She has not had any discomfort with swallowing since surgery, and nowadays, there is not any recurrence and metastasis being detected. Conclusion: It is minimal invasive and simple to enucleate the cervical ELS and patch the defect of esophagus with sternohyoid muscle flap. For some selected patients, this method may be a promising surgical procedure to achieve both good swallowing function and satisfying prognosis.

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Thoracoscopic Esophagectomy for a Huge Leiomyosarcoma

Abstract: Esophageal leiomyosarcoma is the commonest of all esophageal sarcomas but yet has a very low incidence. These tumors have been resected by the open approach so far. We describe the steps and challenges involved in the thoracoscopic excision of a huge leiomyosarcoma of the esophagus.

Cited by 3 publications

References 9 publications

Leiomyosarcoma of stomach extending to gastroesophageal junction and distal esophagus as a rare cause of dysphagia -A case report

Leiomyosarcoma of stomach extending to gastroesophageal junction and distal esophagus as a rare cause of dysphagia -A case report

Histopathological landscape of rare oesophageal neoplasms

Reconstruction of the Esophagus with Sternohyoid Flap after Resection of a Large Cervical Esophageal Leiomyosarcoma

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