Thorn-like TiO2 nanoarrays with broad spectrum antimicrobial activity through physical puncture and photocatalytic action

Abstract

To overcome the conventional limitation of TiO2 disinfection being ineffective under light-free conditions, TiO2 nanowire films (TNWs) were prepared and applied to bacterial disinfection under dark and UV illumination. TNW exhibited much higher antibacterial efficiencies against Escherichia coli (E. coli) under dark and UV illumination conditions compared to TiO2 nanoparticle film (TNP) which was almost inactive in the dark, highlighting the additional contribution of the physical interaction between bacterial membrane and NWs. Such a physical contact-based antibacterial activity was related to the NW geometry such as diameter, length, and density. The combined role of physical puncture and photocatalytic action in the mechanism underlying higher bactericidal effect of TNW was systematically examined by TEM, SEM, FTIR, XPS, and potassium ion release analyses. Moreover, TNW revealed antimicrobial activities in a broad spectrum of microorganisms including Staphylococcus aureus and MS2 bacteriophage, antibiofilm properties, and good material stability. Overall, we expect that the free-standing and antimicrobial TNW is a promising agent for water disinfection and biomedical applications in the dark and/or UV illumination.

Antifungal activity of TiO2/AgBr nanocomposites on some phytopathogenic fungi

“…In other research, the Fedoped TiO 2 /bamboo exhibited a much higher inhibition ability to mold fungi compared with original bamboo and TiO 2 /bamboo, under the natural environment (Li et al, 2017). Based on Kim et al (2019) results, thorn-like TiO 2 nanoarrays physically punctured the cell membrane of bacteria.…”

“…Based on Kim et al. (2019) results, thorn‐like TiO 2 nanoarrays physically punctured the cell membrane of bacteria.…”

Effects of Structural Factors of Hydrated TiO2 on Rutile TiO2 Pigment Preparation via Short Sulfate Process

“…Researches show that the hydrated TiO 2 is colloidal particles, formed by nuclei growing and aggregating, and eventually forming the secondary aggregated particles with the particle size of 10-200 μm 5,6 . Many researchers have widely investigated the hydrolysis process and conditions, effects of the additives and hydrolysis parameters on the products, as well as properties and applications of titanium dioxide [7][8][9][10][11][12][13][14][15][16] . Urakaev et al investigated the homogeneous nucleation and growth of monodispersed spherulites of sulphur and hydrated titanium dioxide of anatase modification by a new coherent optical method for measurement of the relative scattering coefficient based on alternative use of laser radiation of various wavelengths 17 .…”

Antibacterial Activity of Positively and Negatively Charged Hematite (α-Fe2O3) Nanoparticles to Escherichia coli, Staphylococcus aureus and Vibrio fischeri

“…In addition, different types of bacteria demonstrate variable susceptibility to NPs [ 5 , 6 ]. The most efficient antimicrobial metal oxide NPs are CuO [ 7 , 8 ], Cu 2 O [ 7 , 9 ], Ag 2 O [ 10 ], Ag 4 O 4 [ 11 , 12 ], ZnO [ 1 , 13 ], TiO 2 [ 1 , 14 ], and also MgO [ 15 , 16 ]. In addition to potential antimicrobial applications, iron oxide NPs have gained attention for their use in biomedicine for targeted drug delivery, magnetic resonance imaging, and as possible anticancer agents [ 17 , 18 , 19 , 20 , 21 , 22 , 23 ].…”