Sudan is famous for livestock production all over the world. Nevertheless, livestock production was faced by a lot of obstacles. This paper focuses on identifying these barriers. Holistic overview of the past, present and future challenges of sustainable livestock production was used to identify these constraints. They can be summed up into natural and man -made factors which are interacting together to hinder sustainable management of both animals as well as range resources of the country. Natural factors can be summarized as follows: most of range resources of the range resources of Sudan in semi-arid and sensitive fragile areas, alternating dry and wet periods, desertification, climate changes, pests and diseases, soil types and geomorphological factors. While man made factors can be grouped into: local culture, conflicts between herders and cultivators, seasonal bush fires, dissolution of native administration, nomadic tribes coming from neighbouring countries, poor range management, grazing systems adopted, etc.From the other hand, the above mentioned constraints have resulted in negative socioeconomic impacts such as loss of herds, migration of herders to the outskirts of the neighbouring urban centres , socio-cultural changes, family disintegration and lack of essential livelihood services, etc. Sustainable livestock production can be attained through changes in the prevailing local cultures that the number of animals is the source of political power and social prestige, adoption of sustainable practices that help in reducing overgrazing and range deterioration, rehabilitation of fire lines and strengthening the role of local institutions for adopting indigenous cultural practices, etc.