2001
DOI: 10.1055/s-2001-11670
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Three Cases of Fistulae Arising from Gastrointestinal Tract Treated with Endoscopic Injection of Histoacryl®

Abstract: Treatment of gastrointestinal fistula usually consists of conservative management and surgery as definite therapeutic measure. Histoacryl can be used to treat gastrointestinal fistula with no response to conservative management in surgically high-risk patients. We report here three cases of gastrointestinal fistula successfully treated with endoscopic injection of Histoacryl through a catheter into the internal opening and fistulous tract.

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Cited by 47 publications
(10 citation statements)
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“…In comparison to coverage to lead to natural sealing of a defect, complete closure of a leak or fistula is more challenging. Endoscopic injection of Histoacryl [ 28 ] or suturing devices [ 29 ] have been introduced to close post-bariatric leaks or revisions. Recently, the use of fibrin sealants or an over-the-scope clip (OTSC ® ; Ovesco AG, Tübingen, Germany) has been considered the main strategy to close a leak or fistula after bariatric surgery.…”
Section: Leak and Fistulamentioning
confidence: 99%
“…In comparison to coverage to lead to natural sealing of a defect, complete closure of a leak or fistula is more challenging. Endoscopic injection of Histoacryl [ 28 ] or suturing devices [ 29 ] have been introduced to close post-bariatric leaks or revisions. Recently, the use of fibrin sealants or an over-the-scope clip (OTSC ® ; Ovesco AG, Tübingen, Germany) has been considered the main strategy to close a leak or fistula after bariatric surgery.…”
Section: Leak and Fistulamentioning
confidence: 99%
“…Five patients (56%) presented with a proximal staple-line leak (at the angle of His), 3 (33%) with an anastomotic leak and 1 (11%) with leaks at both sites. Median time between surgery and first endoscopy was 12 days (IQR [10][11][12][13][14][15][16][17][18][19] and the median number of therapeutic endoscopic sessions was 3 (IQR 2-6). All patients were treated with fully covered stents for a median period of 26 days (IQR 11-30).…”
Section: Postoperative Leak Groupmentioning
confidence: 99%
“…These goals may be achieved by deploying fully covered self-expanding metal stents (FC-SEMS) [8][9][10][11][12][13]. Other strategies including over the scope clips, fibrin glue, endoscopic suturing and intragastric drainage (IGD) with double pigtail stent have been all described with variable success rate [9,[14][15][16][17]. In cases of chronic leak with perigastric collection formation, the preferred and effective endoscopic approach is to enable adequate drainage of the perigastric collection into the stomach by dissecting the septum separating the two cavities (septotomy) [18] or by inserting double pigtail stent.…”
Section: Introductionmentioning
confidence: 99%
“…These goals may be achieved by deploying fully covered self-expanding metal stents (FC-SEMS) [8][9][10][11][12][13]. Other strategies including over the scope clips (OTSC), fibrin glue, endoscopic suturing and intragastric drainage (IGD) with double pigtail stent (DPS) have been all described with variable success rate [9,[14][15][16][17]. In cases of chronic leak with perigastric collection formation, a typical complication of laparoscopic sleeve gastrectomy (LSG), the preferred (an effective) endoscopic approach is to enable adequate drainage of the perigastric collection into the stomach by dissecting the septum separating the two cavities (septotomy), and to reduce the intragastric pressure by realignment of the sleeve axis using pneumatic balloon dilatation [18].…”
Section: Introductionmentioning
confidence: 99%