Three cases of perioral dermatitis related to fusobacteria treated with β-lactam antibiotics

Ishiguro, Naoko; Maeda, Azusa; Suzuki, Kaoru; Yamana, Yayoi; Fukuya, Yasuko; Kawashima, Makoto

doi:10.3109/09546634.2012.757284

Cited by 10 publications

(9 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…6 Fusobacteria has been implicated in the pathogenesis of perioral dermatitis successfully treated with b-lactam antibiotics in those who were tetracycline-intolerant. 7 2 Fungal organisms: Proliferation of malassezia furfur, otherwise a healthy skin commensal, plays an important etiopathogenic role in the development of seborrheic dermatitis 8 as well as pityrosporum folliculitis, a clinical mimic of acne. 9,10…”

Section: Skin Microbiomementioning

confidence: 99%

The “Maskne” microbiome – pathophysiology and therapeutics

Teo¹

2021

Int J Dermatology

View full text Add to dashboard Cite

“Maskne” is a new term coined during the 2020 COVID‐19 pandemic. It refers to a subset of acne mechanica, deserving consideration in view of widespread reusable fabric mask‐wearing to control the pandemic worldwide. Understanding of underlying pathophysiology directly relates to the novel skin microenvironment and textile–skin friction created by mask‐wearing, distinct from nontextile‐related acne mechanica previously linked to wearing of headgear. Specifically, the occlusive microenvironment leads to microbiome dysbiosis, which is linked to various dermatological conditions. Additional textile–skin interactions include factors such as breathability, stickiness sensations, moisture saturation, and hygiene maintenance. Increased skin temperatures can trigger sweat/heat‐related dermatoses, and ear loops potentially trigger pressure‐induced dermatoses. Important therapeutic considerations include increased skin irritation potential of conventional acne treatments under occlusion, exacerbation of chronic dermatoses, that is, perioral dermatitis, rosacea, and eczema, and susceptibility of these same patient groups to heightened discomfort with mask‐wearing. Cotton, as the traditional fabric of choice for dermatology patients, has limited benefits in the context of face masks – increased subjective discomfort relates to increased moisture saturation and stickiness, inevitable because of high biofluid load of the nasal and oral orifices. Prolonged textile–skin contact time, directly proportional to the risk of maskne, can be an opportunity for the application of biofunctional textiles.

show abstract

Section: Skin Microbiomementioning

confidence: 99%

The “Maskne” microbiome – pathophysiology and therapeutics

Teo¹

2021

Int J Dermatology

View full text Add to dashboard Cite

show abstract

“…Patients showed improvement after one to two weeks and were markedly improved, or their disease was resolved after two to five weeks, with no side effects of treatment. All patients were positive for fusobacteria before treatment but were negative afterward 22 . While further studies are needed with larger control groups, nevertheless there are signals that point toward a possible association between fusobacteria and POD.…”

Section: Infectionmentioning

confidence: 88%

“…18 In a separate study, three patients with POD were treated with cefcapene pivoxil hydrochloride hydrate 100-300 mg/day. 22 Patients showed improvement after one to two weeks and were markedly improved, or their disease was resolved after two to five weeks, with no side effects of treatment. All patients were positive for fusobacteria before treatment but were negative afterward.…”

Section: Bacteriamentioning

confidence: 93%

“…Clinicians and dermatologists must be aware of this risk and prescribe and advise their patients accordingly. Some researchers have posited infectious sources as a cause of POD such as fusobacteria, 17,18,22,23 Demodex folliculorum mites, 24 and…”

Section: Inhaled Corticosteroidsmentioning

confidence: 99%

“…All patients were positive for fusobacteria before treatment but were negative afterward. 22 While further studies are needed with larger control groups, nevertheless there are signals that point toward a possible association between fusobacteria and POD.…”

Section: Bacteriamentioning

confidence: 99%

See 2 more Smart Citations

Perioral dermatitis: Diagnosis, proposed etiologies, and management

Searle

Ali

Al‐Niaimi

2021

J of Cosmetic Dermatology

View full text Add to dashboard Cite

Perioral dermatitis (POD, also referred to as periorificial dermatitis) is an inflammatory and chronic papulopustular and vesicular dermatitis often affecting children and middle-aged females. 1 Topical or systemic treatment is often used, in addition to identifying the likely cause. 1 The granulomatous form of POD is a more typical presentation in those of African-American ethnicity. 2 In terms of etiology, most dermatologists are aware of its association with corticosteroid use, but less is known about other associations such as infective causes, certain cosmetic products, disruptive skin barrier, dental fillings, and toothpaste reactions. In terms of treatment, options range from topical, systemic or conservative, depending on cause, severity, and patient's choice. 3 In this systematic review, we explore the diagnosis of POD, possible etiologies, and treatment options. | ME THODSUsing the keywords "corticosteroids," "dermatology," "fusobacteria," "perioral dermatitis," and "periorificial dermatitis," we searched the databases PubMed, MEDLINE, and EMBASE and identified pertinent English language only literature. Our review was conducted in January 2021, and the time period of evidence was collected from the inception of these databases till January 1, 2021. We appraised the level of evidence, utilizing the Oxford Centre of Evidence-Based

show abstract