Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments

Yasuno, Yoshiaki; Madjarova, Violeta; Makita, Shuichi; Akïba, Masahiro; Morosawa, Atsushi; Chong, Changho; Sakai, Toru; Chan, Kinpui; Itoh, Masahide; Yatagai, Toyohiko

doi:10.1364/opex.13.010652

Cited by 338 publications

(212 citation statements)

References 35 publications

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“…Adequate protocols have allowed us obtaining images of the iridocorneal angle, despite high attenuation of light by the sclera, of similar quality to those previously demonstrated at 1300 nm [38]. Additionally higher scattering of 800 nm light comparing to 1300 nm enables visualization of internal structure of the crystalline lens in young and healthy subjects.…”

Section: Discussionmentioning

confidence: 85%

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Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera

Grulkowski¹,

Gora²,

Szkulmowski³

et al. 2009

Opt. Express

154

124

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Abstract:We describe a new ultrahigh speed Spectral OCT instrument making use of a CMOS camera and demonstrate high quality in vivo imaging of the anterior segment of the human eye. The high flexibility of the designed imaging system allows a wide range of imaging protocols. Two-and three-dimensional high quality OCT images of the cornea, the anterior chamber and the crystalline lens are presented. A high acquisition rate, up to 135,000 A-scans/second enables three-dimensional reconstruction of the anterior segment during lenticular accommodation, blinking and pupillary reaction to light stimulus. We demonstrate OCT tomographic real time imaging of the lens dynamics during accommodation and high quality OCT cross-sectional images of the entire anterior segment of the eye from the cornea up to posterior part of the crystalline lens. 2009 Optical Society of America

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Section: Discussionmentioning

confidence: 85%

“…Possible applications to optometry such as contact lens fit to and its movement on the eye surface were demonstrated by video-rate and three-dimensional imaging performed with the spectral optical coherence tomography [37]. New tunable light sources have been reported for anterior segment OCT imaging [38][39][40][41][42].…”

Section: Introductionmentioning

confidence: 99%

Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera

Grulkowski¹,

Gora²,

Szkulmowski³

et al. 2009

Opt. Express

154

124

View full text Add to dashboard Cite

show abstract

“…Over the past two decades, OCT [6] has proven its clinical value for imaging the eye and for providing two-dimensional (2-D) and three-dimensional (3-D) non-invasive in vivo biopsies of anterior eye segments [7,8] and the retina [9][10][11][12]. Moreover, one-micrometer wavelength systems have demonstrated an enhanced ability to penetrate deeper into the choroid when compared to 800 nm systems [13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Variable velocity range imaging of the choroid with dual-beam optical coherence angiography

Jaillon¹,

Makita²,

Yasuno³

2011

Opt. Express

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Abstract:In this study, we present dual-beam Doppler optical coherence angiography with variable beam separation. Altering beam distance, independently of the scanning protocol, provides a flexible way to select the velocity range of detectable blood flow. This system utilized a onemicrometer wavelength light source to visualize deep into the posterior eye, i.e., the choroid. Two-dimensional choroidal vasculature maps of a human subject acquired with different beam separations, and hence with several velocity ranges, are presented. Combining these maps yields a semiquantitative visualization of axial velocity of the choroidal circulation. The proposed technique may be useful for identifying choroidal abnormalities that occur in pathological conditions of the eye. choroidal vessels using ultrahigh resolution ophthalmic OCT at 1050 nm," Opt. Express 11(17), 1980-1986 (2003 4545-4552 (2008). ©2011 Optical Society of America

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“…Instead of using a spectrometer as in spectral-domain OCT, swept-source OCT uses a monochromatic tunable fast scanning laser source and a photodetector to detect wavelength-resolved interference signal. 23,24 The CASIA OCT (Tomey, Nagoya, Japan) is a commercially available swept-source OCT designed specifically for anterior segment imaging. The wavelength of the swept-source laser is 1310 nm.…”

Section: Reliability Of Anterior Segment Oct For Measurement Of the Amentioning

confidence: 99%

Anterior chamber angle imaging with optical coherence tomography

Leung

Weinreb

2011

Eye

105

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The technology of optical coherence tomography (OCT) has evolved rapidly from time-domain to spectral-domain and swept-source OCT over the recent years. OCT has become an important tool for assessment of the anterior chamber angle and detection of angle closure. Improvement in image resolution and scan speed of OCT has facilitated a more detailed and comprehensive analysis of the anterior chamber angle. It is now possible to examine Schwalbe's line and Schlemm's canal along with the scleral spur. High-speed imaging allows evaluation of the angle in 3601. With three-dimensional reconstruction, visualization of the iris profiles and the angle configurations is enhanced. This article summarizes the development and application of OCT for anterior chamber angle measurement, detection of angle closure, and investigation of the pathophysiology of primary angle closure.

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Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments

Cited by 338 publications

References 35 publications

Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera

Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera

Variable velocity range imaging of the choroid with dual-beam optical coherence angiography

Anterior chamber angle imaging with optical coherence tomography

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