The particle size and morphology of crushed stones impact their macroscopic mechanical and physical properties, which has become a hot topic in the study of road and geotechnical engineering. However, some reported studies fail to control the particle morphology as the only independent variable. This paper presented a new method to print artificial aggregates based on 3D printing technology of particles. The applicability of the new method was verified with uniaxial compression and dynamic modulus tests of asphalt mixtures formed by the printing aggregates. Results showed that the printing aggregates earned similar physical properties to real coarse when sintered at 1400℃ with alumina ceramic powder and CuO: TiO2 a 1:2 additive in mass. Besides, the gross volume density, compressive strength, and shrinkage of the printing aggregates show a similar trend of increasing and then decreasing with the increase of additives. The optimal mass percentage of additives was obtained to be 5%. Mechanical tests indicated that the mechanical indexes of the asphalt mixtures formed with the two types of coarse aggregates were similar, while the results of the specimens formed with artificial coarse aggregates showed less dispersion. The stability of test results was significantly improved for different asphalt mixture specimens prepared with 3D printed coarse aggregate. This provides a basic method for further research on the multi-scale properties of particle material.