Three-Dimensional Echocardiography Assessment of Right Ventricular Volumes and Function: Technological Perspective and Clinical Application

Ahmad, Ashfaq; Li, He; Zhang, Yanting; Liu, Juanjuan; Gao, Ying; Qian, Mingzhu; Yi, Lingling; Zhang, Li; Li, Yuman; Xie, Mingxing

doi:10.3390/diagnostics12040806

Cited by 9 publications

(2 citation statements)

References 114 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Eventually, due to RV structural complexity, 3D echocardiography is currently used as an accurate and reliable method for RV function evaluation compared to above 2D based methods. Studies showed strong correlation between 3D echocardiography and CMR RV volume and function [9].…”

Section: Rv Functionmentioning

confidence: 96%

Right ventricular dysfunction in cancer patients; Is it real or dilemma? A narrative review

Mina¹

2023

J Clin Images Med Case Rep

View full text Add to dashboard Cite

show abstract

Section: Rv Functionmentioning

confidence: 96%

Right ventricular dysfunction in cancer patients; Is it real or dilemma? A narrative review

Mina¹

2023

J Clin Images Med Case Rep

View full text Add to dashboard Cite

show abstract

“…This intricate process is instigated by the heightened afterload imposed on the RV, ultimately culminating in the manifestation of right heart failure and consequential mortality ( 3 ). Prior investigations have substantiated the pivotal role of RV function as a significant prognostic determinant in patients afflicted by PH, irrespective of the diverse etiological factors underlying the condition ( 4 ). Given the continuous nature of the circulatory system and the holistic nature of the left and right ventricles, which are determined by the presence of a shared septum and pericardial constraints, the interdependence of the RV and left ventricles (LV) is a factor that requires consideration ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Non-invasive imaging techniques for early diagnosis of bilateral cardiac dysfunction in pulmonary hypertension: current crests, future peaks

Ahmad,

Zou,

Zhang

et al. 2024

Front. Cardiovasc. Med.

Self Cite

View full text Add to dashboard Cite

Pulmonary arterial hypertension (PAH) is a chronic and progressive disease that eventually leads to heart failure (HF) and subsequent fatality if left untreated. Right ventricular (RV) function has proven prognostic values in patients with a variety of heart diseases including PAH. PAH is predominantly a right heart disease; however, given the nature of the continuous circulatory system and the presence of shared septum and pericardial constraints, the interdependence of the right and left ventricles is a factor that requires consideration. Accurate and timely assessment of ventricular function is very important in the management of patients with PAH for disease outcomes and prognosis. Non-invasive modalities such as cardiac magnetic resonance (CMR) and echocardiography (two-dimensional and three-dimensional), and nuclear medicine, positron emission tomography (PET) play a crucial role in the assessment of ventricular function and disease prognosis. Each modality has its own strengths and limitations, hence this review article sheds light on (i) ventricular dysfunction in patients with PAH and RV–LV interdependence in such patients, (ii) the strengths and limitations of all available modalities and parameters for the early assessment of ventricular function, as well as their prognostic value, and (iii) lastly, the challenges faced and the potential future advancement in these modalities for accurate and early diagnosis of ventricular function in PAH.

show abstract

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

Qu,

Duan,

Chen

2024

ESC Heart Failure

View full text Add to dashboard Cite

With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF). In addition, right HF (RHF) is a common complication associated with various diseases, including congenital heart disease, myocardial infarction (MI), pulmonary arterial hypertension (PAH) and dilated cardiomyopathy (DCM), and it can manifest at any time after left ventricular assist devices (LVADs). The sodium–glucose cotransporter 2 (SGLT2) inhibition by gliflozins has emerged as a cornerstone medicine for managing type 2 diabetes mellitus (T2DM) and HF, with an increasing focus on its potential to enhance RV function. In this review, we aim to present an updated perspective on the pleiotropic effects of gliflozins on the right ventricle and offer insights into the underlying mechanisms. We can ascertain their advantageous impact on the right ventricle by discussing the evidence obtained in animal models and monumental clinical trials. In light of the pathophysiological changes in RHF, we attempt to elucidate crucial mechanisms regarding their beneficial effects, including alleviation of RV overload, reduction of hyperinsulinaemia and inflammatory responses, regulation of nutrient signalling pathways and cellular energy metabolism, inhibition of oxidative stress and myocardial fibrosis, and maintenance of ion balance. Finally, this drug class's potential application and benefits in various clinical settings are described, along with a prospective outlook on future clinical practice and research directions.

show abstract

Three-Dimensional Echocardiography Assessment of Right Ventricular Volumes and Function: Technological Perspective and Clinical Application

Cited by 9 publications

References 114 publications

Right ventricular dysfunction in cancer patients; Is it real or dilemma? A narrative review

Right ventricular dysfunction in cancer patients; Is it real or dilemma? A narrative review

Non-invasive imaging techniques for early diagnosis of bilateral cardiac dysfunction in pulmonary hypertension: current crests, future peaks

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

Contact Info

Product

Resources

About