Three-dimensional eye motion correction by Lissajous scan optical coherence tomography

Chen, Yiwei; Hong, Young-Joo; Makita, Shuichi; Yasuno, Yoshiaki

doi:10.1364/boe.8.001783

Cited by 47 publications

(27 citation statements)

References 22 publications

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“…Only large lateral motion and blinking cannot be compensated and, therefore, such an invalid data set must be excluded from evaluation. Faster acquisition and the use of a Lissajous scanning pattern 33 might allow for further reduction and compensation of motion artifacts, but would either increase the cost of the system or complicate post-processing.…”

Section: Discussionmentioning

confidence: 99%

Mapping of Corneal Layer Thicknesses With Polarization-Sensitive Optical Coherence Tomography Using a Conical Scan Pattern

Beer

Wartak

Pircher

et al. 2018

Invest. Ophthalmol. Vis. Sci.

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PURPOSE. We demonstrate segmentation and mapping of corneal layers (epithelium, Bowman's layer, and stroma) across the entire cornea (limbus to limbus), using additional contrast provided by polarization-sensitive optical coherence tomography (PS-OCT) and analyze the reproducibility of the procedure. METHODS. A custom built PS-OCT system operating at 1045 nm central wavelength with conical scanning was used for image acquisition. Conical scanning allows for almost perpendicular beam incidence on the corneal surface and provides good signal quality over the entire field of view. Epithelium, Bowman's layer, and stroma were segmented using the additional contrast provided by PS-OCT. Thickness maps were computed and analyzed in sectors. Both eyes of 20 healthy volunteers were imaged at least three times to test this method and to quantify reproducibility. RESULTS. Thickness maps of the epithelium show significant (P < 0.001) superior thinning and an inferior thickening. Bowman's layer appears homogeneous within the central 7 to 8 mm diameter of the cornea and gets thinner toward the periphery until this layer disappears between 4 and 5.5 mm eccentricity from the center. Intersubject variations of the measured thicknesses of epithelium (coefficient of variation [CV]~8%), Bowman's layer (CV~25%), and stroma (CV~10%) were observed. Very good reproducibility of thickness measurements of epithelium (CV < 3%), Bowman's layer (CV < 5%), and stroma (CV < 2%) was found. Furthermore, a significant correlation (P < 0.001) between layer thicknesses of the right and left eyes of the same subject was found. CONCLUSIONS. PS-OCT with conical scanning is a feasible approach for determining thickness maps of corneal layers on a large field of view with high reproducibility.

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Section: Discussionmentioning

confidence: 99%

Mapping of Corneal Layer Thicknesses With Polarization-Sensitive Optical Coherence Tomography Using a Conical Scan Pattern

Beer

Wartak

Pircher

et al. 2018

Invest. Ophthalmol. Vis. Sci.

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“…Chen et al [84] (2017) proposed an imaging method based on Lissajous scanning and a respective motion correction algorithm. Lissajous scan is a closed-loop scan obtained by operating along the horizontal and vertical axes using sinusoidal waveforms of different frequencies.…”

Section: [2015-2018]mentioning

confidence: 99%

Review on Retrospective Procedures to Correct Retinal Motion Artefacts in OCT Imaging

et al. 2019

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Motion artefacts from involuntary changes in eye fixation remain a major imaging issue in optical coherence tomography (OCT). This paper reviews the state-of-the-art of retrospective procedures to correct retinal motion and axial eye motion artefacts in OCT imaging. Following an overview of motion induced artefacts and correction strategies, a chronological survey of retrospective approaches since the introduction of OCT until the current days is presented. Pre-processing, registration, and validation techniques are described. The review finishes by discussing the limitations of the current techniques and the challenges to be tackled in future developments.

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“…However, these methods naturally double the data acquisition time, which causes inconvenience to patients. In another recent study, Lissajous scanning OCT was developed to compensate eye motion using a single volume data [26,27]. It compensates eye motion using overlapped positions of the trajectory of the Lissajous scan.…”

Section: Introductionmentioning

confidence: 99%

Cross‐scanning optical coherence tomography angiography for eye motion correction

Kim

Song

Choi

et al. 2020

Journal of Biophotonics

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We propose a cross‐scanning optical coherence tomography (CS‐OCT) system to correct eye motion artifacts in OCT angiography images. This system employs a dual‐illumination configuration with two orthogonally polarized beams, each of which simultaneously perform raster scanning in perpendicular direction with each other over the same area. In the reference arm, a polarization delay unit is used to acquire the two orthogonally polarized interferograms with a single photo detector by introducing different optical delay lines. The two cross‐scanned volume data are affected by the same eye motion but in two orthogonal directions. We developed a motion correction algorithm, which removes artifacts in the slow axis of each angiogram using the other and merges them through a nonrigid registration algorithm. In this manner, we obtained a motion‐corrected angiogram within a single volume scanning time without additional eye‐tracking devices.

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Three-dimensional eye motion correction by Lissajous scan optical coherence tomography

Cited by 47 publications

References 22 publications

Mapping of Corneal Layer Thicknesses With Polarization-Sensitive Optical Coherence Tomography Using a Conical Scan Pattern

Mapping of Corneal Layer Thicknesses With Polarization-Sensitive Optical Coherence Tomography Using a Conical Scan Pattern

Review on Retrospective Procedures to Correct Retinal Motion Artefacts in OCT Imaging

Cross‐scanning optical coherence tomography angiography for eye motion correction

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