This paper focuses on the three-dimensional (3D) asymmetric problem of functionally graded (FG) truncated conical shell subjected to thermal field and inertia force due to the rotating part. The FG properties are assumed to be varied along the thickness according to power law distribution, whereas Poisson’s ratio is assumed to be constant. On the basis of 3D Green-Lagrange theory in general curvilinear coordinate, the fundamental equations are formulated and then two versions of differential quadrature method (DQM) including polynomial based differential quadrature (PDQ) and Fourier expansion-based differential quadrature (FDQ) are applied to discretize the resulting differential equations. The reliability of the present approach is validated by comparing with known literature where good agreement is reached using considerably few grid points. The effects of different mechanical boundary conditions, temperature fields, rotating angular speed, and shell thickness on the distributions of stress components and displacement in thickness direction for both axisymmetric and asymmetric cases are graphically depicted.