Design and implementation of an energy-efficient protocol is one of the main challenges in wireless sensor networks (WSNs). In terms of localization, both energy efficiency and accuracy must be addressed to achieve the final goals of localization. In mobile sensor nodes, where battery power is the most hardware resource limitation, accurate localization needs to be extremely energy efficient. In this work, a virtual multiple-input multiple-output (VMIMO) technique is deployed to tackle the problems of getting more energy efficiency and higher accuracy simultaneously.In this case, the optimum selection of the number of transceiver nodes can be obtained with the lowest possible total energy consumption, localization error, and speed of nodes. In addition, VMIMO decreases the power of transmitters, and therefore will lead to the reduction of destructive effects of electromagnetic sensitivity (EMS) on the body.