Agricultural rims are highly loaded components which affect the functionality and safety of tractors significantly. For this reason, it is essential to prevent a damage of the rims. However, fatigue-initiated cracks along the bolt circle arise at any time during application. Until now, the determining load for the crack initiation is unclear. The paper investigates this fatigue problem by experimental, analytical, and numerical methods. Therefore, a test rig using hydraulic actuators is designed to load the rim by rotating bending in combination with a lateral force. The loads are deduced by an analytical model of the tractor under different driving situations like cornering. The finite element model shows the critical locations by performing a fatigue analysis of the driving situation. The experimental and numerical results verify the assumption that the rotating bending in combination with a lateral force leads to the fatigue cracks also found by tractors in reality.