“…Keywords: 3D printing, 3D printing materials, Additive manufacturing, Annealing, Autoclave, Medical devices, Optimization, Sterilization, Surgical instruments, Polylactic acid Background 3D printing is currently used in the medical field for a wide variety of purposes, including printing patient-personalized anatomical models to guide surgeons preoperatively, creating in-house anatomical models for medical student and resident training, and printing surgical instruments, prostheses, and implants [1][2][3][4][5][6][7]. 3D printed models have already been adopted to plan surgeries in fields including, but not limited to, cardiothoracic, craniomaxillofacial, hepatic, neonatal, neurological, ophthalmologic, orthopaedic, and plastic surgery [8][9][10][11][12][13][14][15][16][17][18][19]. Therefore, the accuracy of 3D printed models becomes exceedingly important.…”