Three-dimensional RODEO breast MR imaging of lesions containing ductal carcinoma in situ.

Soderstrom, C E; Harms, Steven E.; Copit, Debra S.; Evans, W. Phil; Savino, Daniel A.; Krakos, Patricia A.; Farrell, R. S.; Flamig, Duane P.

doi:10.1148/radiology.201.2.8888235

Cited by 149 publications

(77 citation statements)

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“…Variable enhancement characteristics and also early contrast enhancement in a ductal carcinoma in situ are also known from dynamic MR mammography studies and reported to be related with angiogenesis. 36,37 Some limitations were encountered in our study. Owing to the method of data transfer (see Materials and Methods), a quantitative evaluation of the color hues, encoding for the flow velocities, unfortunately was not available for sensible analysis.…”

mentioning

confidence: 94%

Locally advanced breast carcinoma: computer assisted semiquantitative analysis of color Doppler ultrasonography in the evaluation of tumor response to neoadjuvant chemotherapy (work in progress).

Huber

Medl²,

Helbich³

et al. 2000

Journal of Ultrasound in Medicine

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We aimed to evaluate objectively the value of color Doppler flow imaging in the assessment of response of locally advanced breast cancer to primary medical treatment by using a computer assisted semiquantitative method. Prior to and after neoadjuvant treatment, 17 patients with locally advanced breast carcinoma were prospectively evaluated by physical examination and computer assisted semiquantitative color Doppler ultrasonography. The results of clinical and color Doppler examination were finally correlated to the histopathologic evaluation of tumor response. The degree of concordance between posttherapeutic histopathologic results, clinical examination, and color Doppler assessment was evaluated by kappa statistics. Concordance was 0.474 (0.135‐0.813) between histopathologic results and clinical posttherapeutic assessment and 0.870 (0.627‐1.113) between histopathologic results and semiquantitative color Doppler examination. Objective semiquantitative assessment of tumor vascularity as displayed by color Doppler ultrasonography has potential as a functional tool for measuring tumor response to neoadjuvant chemotherapy.

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mentioning

confidence: 94%

Locally advanced breast carcinoma: computer assisted semiquantitative analysis of color Doppler ultrasonography in the evaluation of tumor response to neoadjuvant chemotherapy (work in progress).

Huber

Medl²,

Helbich³

et al. 2000

Journal of Ultrasound in Medicine

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“…DWI findings were evaluated in consideration of these three groups. We calculated cut-off ADC values to distinguish malignant and benign lesions from complicated cysts/abscesses (0.6x10 -3 cm 2 /sec) and also malignant (10)(11)(12) . The contrast enhancement dynamics of the lesion reflects the vascularity of the tissue, the vascular permeability, the interstitial pressure changes and the contents of extracellular spaces.…”

Section: Resultsmentioning

confidence: 99%

Role of diffusion-weighted MR Imaging in solid breast masses and complicated cysts

Canverenler¹,

Adıbelli²,

Canverenler³

et al. 2017

Terh

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Objective: The purpose of this study is to evaluate the characteristics of malign/benign lesions and complicated cysts/abscesses in diffusion weighted magnetic resonance imaging and to investigate the contribution of apparent diffusion coefficient (ADC) to differential diagnosis. Methods: In this retrospective study; histopathologically proven 177 lesions (21 complicated cysts, 91 malign and 65 bening lesions) were evaluated in 116 women using conventional MRI and diffusion weighted imaging (DWI /sec (P<0.001), respectively. The ADC values identified for complicated cysts/abscesses are significantly lower than the ADC values of benign and malign values reported in the literature. Conclusion: As a result, the specificity, positive predictive value and negative predictive value of DWI when it is used alone are higher than conventional MRI, while sensitivity of DWI is nearly the same. DWI is effective in detecting breast lesions and also ADC value is useful in distinguishing among complicated cysts/abscesses, malignant and benign breast lesions.

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“…By the use of MR, lesions can be identified that are not seen mammographically. But the method of MR-guided needle biopsy of the breast is still too complicated for routine use [31][32][33][34][35]. Although there is the possibility of using ultrasound or MR as guidance modalities for minimally invasive biopsy of DCIS, stereotactic mammography seems to be the best means of targeting suspicious microcalcifications within the breast.…”

Section: Diagnosismentioning

confidence: 99%

Ductal Carcinoma in situ of the Breast: Diagnosis and Management

Friedrich

Felberbaum

Krämer³

et al. 2003

Oncol Res Treat

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Currently, no precise morphologic or biologic prognostic factors reliably identify patients with ductal carcinoma in situ (DCIS) who are at high risk of disease progression. DCIS is a disease with an extremely favorable prognosis and a small likelihood of dying from breast cancer, regardless of what type of treatment is received. No retrospective or prospective study to date has demonstrated a significant difference in breast cancer specific mortality regardless of treatment. The similarities between DCIS and invasive cancer suggest that an important area for future research should be elucidating the processes that can either unleash or contain the invasive potential of DCIS cells. Thus, an understanding of the biology of DCIS can assist in the prevention, the assessment, and the diagnosis of invasive breast cancer.

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Three-dimensional RODEO breast MR imaging of lesions containing ductal carcinoma in situ.

Abstract: Three-dimensional RODEO MR imaging can be an adjunct to mammography because of its ability to enable better determination of tumor extent and differentiation of pure DCIS from DCIS with an invasive component.

Cited by 149 publications

References 0 publications

Locally advanced breast carcinoma: computer assisted semiquantitative analysis of color Doppler ultrasonography in the evaluation of tumor response to neoadjuvant chemotherapy (work in progress).

Locally advanced breast carcinoma: computer assisted semiquantitative analysis of color Doppler ultrasonography in the evaluation of tumor response to neoadjuvant chemotherapy (work in progress).

Role of diffusion-weighted MR Imaging in solid breast masses and complicated cysts

Ductal Carcinoma in situ of the Breast: Diagnosis and Management

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