This paper presents a method for pursuer to track a moving target in a three-dimensional space. The method is based on the guidance laws combined with the kinematics equations of the pursuer and the target. The maneuvers of the target are prior unknown to the pursuer. Guidance laws used for tracking are the deviated pursuit and the proportional navigation, and the method presents a family of navigation laws resulting in a rich behavior for different parameters. For the three-dimensional scenario, two cases-not presenting interference and presenting interference are considered. In the absence of interference, the control strategy is proposed to implement the problem of tracking. In the presence of interference, an optimal information fusion Kalman filter weighted by scalars and guidance laws are combined to improve the trajectory tracking precision, and the combination can enrich the application range of information fusion and guidance laws. Simulations are conducted to demonstrate the effectiveness and reliability of the proposed control strategy.