Three-Dimensional Trapping and Dynamic Axial Manipulation with Frequency-Tuned Spiraling Acoustical Tweezers: A Theoretical Study

Gong, Zhixiong; Baudoin, Michaël

doi:10.1103/physrevapplied.16.024034

Cited by 15 publications

(8 citation statements)

References 59 publications

(112 reference statements)

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“…Instead, because the acoustic wave propagation is made more complex by the confinement, fully three-dimensional representations may be necessary to accurately describe the flow, even in slow streaming conditions. By introducing complex forms of the acoustic wave that, for example, contains helical propagation components that add in an angular momentum flux in addition to the axially propagating component pioneered by Hefner and Marston (1999) and analyzed in careful detail by Zhang and Marston (2011), it becomes possible to selectively manipulate particles in fluid samples (Jiang et al, 2016;Tian et al, 2019;Gong and Baudoin, 2021), an aspect described later. It is also possible to produce particle concentration in sample droplets suitable for biological samples (Zhang et al, 2021c) with acoustic streaming from spirally propagating acoustic waves, though it does require the use of a different cut of the piezoelectric substrate (Zhang N. et al, 2020), an aspect not often studied in modern acoustofluidics and one in which significant progress could be made into the future.…”

Section: The Details and Applications Of Streamingmentioning

confidence: 99%

Acoustofluidics

Friend

2023

Front. Acoust.

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The propagation of acoustic waves in fluids and solids produces fascinating phenomena that have been studied since the late 1700s and through to today, where it is finding broad application in manipulating fluids and particles at the micro to nano-scale. Due to the recent and rapid increase in application frequencies and reduction in the scale of devices to serve this new need, discrepancies between theory and reality have driven new discoveries in physics that are underpinning the burgeoning discipline. While many researchers are continuing to explore the use of acoustic waves in microfluidics, some are exploring vastly smaller scales, to nanofluidics and beyond. Because many of the applications incorporate biological material—organelles, cells, tissue, and organs—substantial effort is also being invested in understanding how ultrasound interacts with these materials. Surprisingly, there is ample evidence that ultrasound can be used to directly drive cellular responses, producing a new research direction beyond the established efforts in patterning and agglomerating cells to produce tissue. We consider all these aspects in this mini-review after a brief introduction to acoustofluidics as an emerging research discipline.

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Section: The Details and Applications Of Streamingmentioning

confidence: 99%

Acoustofluidics

Friend

2023

Front. Acoust.

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“…2. The angular spectrum simply consists in (i) taking the 2D Fourier transform of the source to transform it into a sum of plane waves, (ii) propagating each plane wave up to the target plane, and (iii) taking the inverse Fourier transform of the sum of the transported plane waves [21].…”

Section: Synthesis Of Focused Beams With Active Hologramsmentioning

confidence: 99%

“…However, these extreme values might not correspond to existing cells. Typical human cells could however be trapped by using single beam tweezers based on a vortex beam [21].…”

Section: Typical Human Cellsmentioning

confidence: 99%

“…With acoustical vortices, 2D trapping of small microparticles [17,18] and cells [19] has also been demonstrated with holographic tweezers based on spiraling interdigitated transducers [20]. Later on, it was theoretically shown [21] that these types of particles could also be trapped in three dimensions with these types of devices. The 3D manipulation of bubbles with axial compensation of the Archimedes force and radiation force with these wave structures was also demonstrated by Baresch et al [22].…”

Section: Introductionmentioning

confidence: 99%

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Single Beam Acoustical Tweezers Based on Focused Beams: A Numerical Analysis of Two-Dimensional and Three-Dimensional Trapping Capabilities

Gong

Baudoin

2022

Phys. Rev. Applied

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Selective single beam tweezers open tremendous perspectives in microfluidics and microbiology for the micromanipulation, assembly, and mechanical properties testing of microparticles, cells, and microorganisms. In optics, single beam optical tweezers rely on tightly focused laser beams, generating a three-dimensional (3D) trap at the focal point. In acoustics, 3D traps have so-far only been reported experimentally with specific wavefields called acoustical vortices. Indeed, many types of particles are expelled (not attracted to) the center of a focused beam. Yet the trapping capabilities of focused beams have so far only been partially explored. In this paper, we numerically explore with an angular spectrum code the trapping capabilities of focused beams on a wide range of parameters (size over wavelength ratio and type of particles). We demonstrate that (i) 3D trapping of particles, droplets, and microorganisms more compressible than the surrounding fluid is possible in and beyond the Rayleigh regime [e.g., polydimethylsiloxane (PDMS), olive oil, benzene, and lipid sphere] and that (ii) 2D trapping (without an axial trap) of particles with positive contrast factor can be achieved by using the particles resonances. The 3D trapping of biocompatible functionalized PDMS particles with integrable, high-frequency focused-beam tweezers opens the way towards acoustic force spectroscopy in some force ranges that were not accessible with optical methods.

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“…The IDT induces localized motion on the surface of the piezoelectric material that transfers momentum to the fluid, inducing a fast acoustic streaming flow. 23,24 Relatively large spiral IDTs have been previously studied as acoustic tweezers, 25,26 where the IDT is placed at the bottom of the liquid container, or for inducing acoustic streaming inside droplets, where the spiral is surrounding the droplet. 13,14,27 When the IDT is external to the droplet, the propagation of the surface acoustic wave on the substrate before interacting with the droplet plays a major role, and the nonuniform propagation velocity and how to compensate it have been studied.…”

Section: Introductionmentioning

confidence: 99%

Acoustic micro‐beam vortex generator for flow actuation inside droplets

Sánchez‐Saldaña,

Fernandino,

Dorao

2024

Droplet

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Controlling acoustic streaming inside a droplet has excellent potential for enabling fluid and particle operations such as mixing, separation, and aggregation in various applications. Most concepts for generating surface acoustic waves are based on the placement of an interdigitated transducer at the side of a droplet, thus externally acting on the droplet. In this case, the flow structure inside the droplet is controlled by the relatively large scale of the interdigitated transducer compared to the droplet, thus limiting the local control of the flow. One possibility to overcome this drawback is to reduce the size of the actuator such that a highly focused ultrasound transducer can induce localized acoustic streaming in space. Here, we introduce a micro‐spiral interdigitated transducer smaller than a droplet size that can generate micro‐size vortices inside the droplet. This step enables a new way of controlling the flow inside the droplet, facilitating mixing, separation, aggregation, and patterning of particles. We study the characteristics of the acoustic streaming and the potential application of the flow for the separation and patterning of particles. The simplicity of the concept provides in‐droplet particle manipulation toolsets for many applications such as biosensing, microbiology, and point‐of‐care devices.

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Three-Dimensional Trapping and Dynamic Axial Manipulation with Frequency-Tuned Spiraling Acoustical Tweezers: A Theoretical Study

Cited by 15 publications

References 59 publications

Acoustofluidics

Acoustofluidics

Single Beam Acoustical Tweezers Based on Focused Beams: A Numerical Analysis of Two-Dimensional and Three-Dimensional Trapping Capabilities

Acoustic micro‐beam vortex generator for flow actuation inside droplets

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