Three‐dimensional ultrasonographic assessment of fetal hands and feet

Hata, Toshiyuki; Aoki, Showa; Akiyama, Masashi; Yanagihara, Toshihiro; Miyazaki, Kohji

doi:10.1046/j.1469-0705.1998.12040235.x

Cited by 44 publications

(31 citation statements)

References 12 publications

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“…Recent scientific publications have shown that current technological advances lead to a broader area of application for the 3D imaging technique in connection with fetal organ analyses; the publications describe the routine depiction of fetal hands [4,5], cephalic [6][7][8][9][10] and vertebral structures [1,[11][12][13], cardiac volume [14], fetal ears [15], liver [16], lung [17], kidneys [18] and amniotic fluid [19]. The advantages and disadvantages of 3D image information compared to 2D imaging show considerable variations and are often a matter for controversial discussion between the different research groups.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Two-Dimensional versus Three-Dimensional Ultrasound in Obstetric Diagnostics: A Prospective Study

Scharf

Ghazwiny²,

Steinborn³

et al. 2001

Fetal Diagn Ther

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Objectives: We aimed to find answers to the following questions: What are the technical and biological prerequisites for easily obtainable three-dimensional (3D) images? What are the visualization rates for various fetal organ systems? What is the potential for assessing fetal malformations? What are the psychological effects of 3D imaging on the expectant mothers? Methods: Between January and June 1998, 433 pregnant women were prospectively examined with two-dimensional (2D) and 3D sonography. Results: 3D visualization in healthy fetuses was inferior in quality to 2D visualization, which also accounted for the comparison of 3D imaging versus 2 D imaging among fetuses affected with malformations. In only 1 case did 3D imaging yield a slightly better description of the given malformation. This did not result in a different therapeutical approach. Concerning the psychological effect of 3D imaging, a marked approval of the 3D method was recorded. Conclusions: These results show that the image information acquired by 3D ultrasound technology is nearly always inferior to the image information obtained by conventional 2D imaging. 3D imaging can be useful for specific malformations under the condition that these examinations be performed in specific ultrasound departments. Thus, a clearly defined range of indications can be assigned to 3D imaging.

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Section: Discussionmentioning

confidence: 99%

“…The advantages and disadvantages of 3D image information compared to 2D imaging show considerable variations and are often a matter for controversial discussion between the different research groups. Thus, the assessment of the quality of 3D image information varies from increased [1,5,20] to comparable [7] to reduced [10].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Two-Dimensional versus Three-Dimensional Ultrasound in Obstetric Diagnostics: A Prospective Study

Scharf

Ghazwiny²,

Steinborn³

et al. 2001

Fetal Diagn Ther

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“…The most frequently observed digit anomaly is polydactyly, which occurs in Trisomy 13 syndrome. Again, ultrasonographically, some findings, such as limb reduction and club or rocker-bottom feet are seen in Trisomy 18 syndrome (Hata et al, 1998). Separately, it is emphasized that the findings, such as the shortness and curling in the mid-phalanx of the 5th digit during the prenatal period, are specific findings for Down's syndrome (Hata et al;.…”

Section: Introductionmentioning

confidence: 96%

“…Again, ultrasonographically, some findings, such as limb reduction and club or rocker-bottom feet are seen in Trisomy 18 syndrome (Hata et al, 1998). Separately, it is emphasized that the findings, such as the shortness and curling in the mid-phalanx of the 5th digit during the prenatal period, are specific findings for Down's syndrome (Hata et al;. Again, hand radiographies are used for determining the body height and age as well as evaluating the development and the maturation of the skeletal system during the postnatal period .…”

Section: Introductionmentioning

confidence: 99%

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A Radiological Investigation on the Hand Development in Human Fetuses Throughout the Fetal Period and an Evaluation Performed in Terms of its Clinical Importance Hand Development

et al. 2016

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CEREN, U.; KADIR, D.; OSMAN, S. & MEHMED ALI, M.A Radiological investigation on the hand development in human fetuses throughout the fetal period and an evaluation performed in terms of its clinical importance. Int. J. Morphol., 34(4):1539Morphol., 34(4): -1552Morphol., 34(4): , 2016. SUMMARY:It was aimed in this study that the morphometric development of the hand in human fetuses throughout the fetal period be radiologically investigated and the clinical importance of this period be evaluated. A total of 50 fetuses with no external pathology or anomaly, and the ages of which varied between 20-40 gestational weeks were incorporated into the study. The fetuses were separated into groups according to gestational weeks, trimesters and months. After the general external measurements of the fetuses were performed, mammography and hand radiographies of the fetuses were shot in the way that their hands would be in a pronational position. Afterwards, the morphometric measurements of the hands were performed with the help of a digital caliper through the hand radiographies that were shot. The averages and standard deviations of the measured parameters were determined according to gestational weeks, trimesters and months. There was a significant correlation between the measured parameters and the gestational age (p<0.001). Additionally, it was observed that there was some difference among the groups in the comparison of the measured parameters involving trimesters and months (p<0.05). We are of the opinion that in evaluating the clinical studies regarding the morphometric development of the hand throughout the fetal period and in determining the pathologies and variations related to the fetal hand development, the data obtained in our study will be of use to the clinicians engaged in gynecology, and forensic medicine as well as those involved in this field.

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Molecular prenatal diagnosis for hereditary distal arthrogryposis type 2B

Jiang¹,

Bian²,

Li³

et al. 2007

Prenatal Diagnosis

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Autosomal dominant distal arthrogryposes (DAs) are a group of muscle diseases characterized by congenital contractures of the limbs. Currently, prenatal diagnosis of DAs depends upon ultrasound examination during late gestation. Recently, five genes encoding fast switch proteins located at 9p13.2, 11p15.5 and 17q13.1 were identified. These included TPM2, TNNI2/TNNT3, and MYH3/MYH8. Last year, we discovered a novel heterozygous mutation c.523_525delAAG (p.K175del) in the TNNI2 gene, which encodes the isoform of troponinI, in a seven-generation Chinese family affected with distal arthrogryposis type 2B (DA2B). Here, we report the molecular prenatal diagnosis of 3 high-risk fetuses of two women in the family by two-point linkage inferential analysis and deletion detection of the TNNI2 gene with chorionic villus sampling (CVS) or amniocentesis. To our knowledge, this is the first description of molecular prenatal diagnosis for DAs.

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Three‐dimensional ultrasonographic assessment of fetal hands and feet

Abstract: Objective The aim of this study was to describe fetal hands and feet using three-dimensional ultrasonography. Design This was a randomized prospective study.Methods Ninety-seven fetuses from 12 to 40 weeks' gestation were studied with a specially developed

Cited by 44 publications

References 12 publications

Evaluation of Two-Dimensional versus Three-Dimensional Ultrasound in Obstetric Diagnostics: A Prospective Study

Evaluation of Two-Dimensional versus Three-Dimensional Ultrasound in Obstetric Diagnostics: A Prospective Study

A Radiological Investigation on the Hand Development in Human Fetuses Throughout the Fetal Period and an Evaluation Performed in Terms of its Clinical Importance Hand Development

Molecular prenatal diagnosis for hereditary distal arthrogryposis type 2B

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