“Three-in-one” platform based on Fe-CDs nanozyme for dual-mode/dual-target detection and NIR-assisted bacterial killing

Abstract

Carbon dots (CDs) as nanozymes have attracted increasing attention for their remarkable properties. However, besides general enzyme activity, the comprehensive properties including photoluminescence and photothermal property have little been explored,...

Advanced nanozymes possess peroxidase-like catalytic activities in biomedical and antibacterial fields: review and progress

“…Yang et al first coordinated Fe ions with EDTA to form chelates, followed by pyrolysis to produce iron-doped CDs (Fe-CDs). 48 Iron doping significantly enhanced the POD activity of Fe-CDs compared to the original CDs. In plate count experiments, the synergistic treatment of Fe-CDs + H 2 O 2 + NIR nearly eradicated 100% of E. coli .…”

Metal-doped carbon dots for biomedical applications: From design to implementation

“… 349/437 [ 47 ] Fe-CDs EDTA, FeCl 3 ⋅6H 2 O Fe-CDs with tunable fluorescence and enhanced peroxidase-like activity have led to the development of a novel "triple-play" multifunctional platform offering dual-mode/dual-target detection and near-infrared (NIR)-assisted antibacterial capabilities. 340/430 [ 48 ] NiO NPs@C-dots benzene-1,4-diamine, Ni(NO 3 ) 2 ⋅6H 2 O The functional groups of NiO NPs@C-dots can increase the efficiency of antibacterial activity due to their interaction with receptor molecules (amino acids) and tend to damage bacterial cells. – [ 49 ] Zn-CDs Ethanol, o -phenylenediamine, L-tryptophan, zinc chloride Zn-CDs maintained the catalytic oxidative properties of zinc metal and improved the bactericidal rate and ROS generation efficiency.…”

Carbon Dots Dually Doped with Fe and Co for Visual Detection of H2O2 and Glutathione

“…19 Fan et al constructed a dual-mode analysis platform for H 2 O 2 and cholesterol using Fe-CDs with POD-like activity. 20 Mo-CDs, Pt-CDs, etc. Inspired by these, this paper designed bimetallic-doped Fe, Co-CDs, which manifested bright promise in dual-mode sensors used in analytical applications.…”

“…Niu et al developed a bimodal ratiometric colorimetric/fluorometric method based on Mn-CDs with oxidase-mimic activity, realizing the determination of nitrite . Fan et al constructed a dual-mode analysis platform for H 2 O 2 and cholesterol using Fe-CDs with POD-like activity . Recently, metal-doped CDs with POD activity emerged in the field of analytical detection, such as Cu-CDs, Mo-CDs, Pt-CDs, etc.…”