Three Japanese Cases of Inflammatory Bowel Disease Associated with Left-sided Colonic Diverticulosis: Its Implication

Association of diverticular colitis and inflammatory bowel disease

“…A close relationship exists between dietary westernization and increased prevalence of colonic diverticulosis 7,10 . Based on these observations, left‐sided (sigmoid colon) diverticulosis can be a symbol of dietary westernization 11 …”

“…The epidemiological phenomena observed in colonic diverticulosis are also observed in inflammatory bowel disease (IBD). IBD is common in developed countries and dietary westernization is thought to be related to the increase of IBD 11,12 . As both colonic diverticulosis with or without colitis and IBD are mediated by a westernized diet, they could be associated.…”

“…As both colonic diverticulosis with or without colitis and IBD are mediated by a westernized diet, they could be associated. We described three such cases of IBD associated with sigmoid colon diverticulosis; two cases, a 85‐year‐old man and a 73‐year‐old woman, with UC; and one case, a 77‐year‐old woman, with CD 11 . Three of 23 patients with diverticular colitis developed UC later 1 and two of 25 patients who had sigmoid resection for diverticular colitis developed CD later 2 .…”

“…7,10 Based on these observations, left-sided (sigmoid colon) diverticulosis can be a symbol of dietary westernization. 11 The epidemiological phenomena observed in colonic diverticulosis are also observed in inflammatory bowel disease (IBD). IBD is common in developed countries and dietary westernization is thought to be related to the increase of IBD.…”

“…IBD is common in developed countries and dietary westernization is thought to be related to the increase of IBD. 11,12 As both colonic diverticulosis with or without colitis and IBD are mediated by a westernized diet, they could be associated. We described three such cases of IBD associated with sigmoid colon diverticulosis; two cases, a 85-year-old man and a 73-year-old woman, with UC; and one case, a 77-year-old woman, with CD.…”