Three New Cases of Melioidosis, Guadeloupe, French West Indies

Melot, Bénédicte; Bastian, Sylvaine; Valade, Eric; Gorgé, Olivier; Flèche, Anne Le; Idier, Charlotte; Vernier, M.; Fernandes, Elisabeth; Hoën, Bruno; Breurec, Sébastien; Carlès, Michel

doi:10.3201/eid2603.190718

Cited by 7 publications

(8 citation statements)

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“…pseudomallei in Les Saintes, Guadeloupe. They also support the hypothesis of a local contamination of two cases of human melioidosis reported on the island in 1997 (a tourist that visited Les Saintes for 3 weeks) [25] and in 2016 (a local resident) [23]. Importantly, the MLST profile of the strain isolated from our study (ST92) was identical to that of the 1997 human case [23].…”

Section: Discussionsupporting

confidence: 88%

“…They also support the hypothesis of a local contamination of two cases of human melioidosis reported on the island in 1997 (a tourist that visited Les Saintes for 3 weeks) [25] and in 2016 (a local resident) [23]. Importantly, the MLST profile of the strain isolated from our study (ST92) was identical to that of the 1997 human case [23]. In the Burkholderia pseudomallei PubMLST database, ST92 was identified in nine human strains: one from a Swiss traveler to Martinique [21], one from Puerto Rico, two from Mexico [48], and five from Brazil [49], illustrating the restricted spatial distribution of this sequence type.…”

Section: Discussionsupporting

confidence: 80%

“…Cases of melioidosis have been reported in both South, Central and North America. This includes the French West Indies, i.e., Guadeloupe and Martinique, where 21 human cases have been recorded since 1993 [21][22][23][24][25], some of whom had no history of travel to endemic areas. In contrast, no human cases have been reported in French Guiana (Guiana Shield, South America), while human cases have been reported in neighboring Brazil [3], as well as in Venezuela and Colombia [26].…”

Section: Introductionmentioning

confidence: 99%

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Serological screening in animals combined with environmental surveys provides definite proof of the local establishment ofBurkholderia pseudomalleiin Guadeloupe

Gasqué,

Guernier-Cambert,

Manuel

et al. 2024

Preprint

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Background: Melioidosis is an emerging infectious disease caused by the soil-dwelling bacterium Burkholderia pseudomallei that affects both humans and animals. It is endemic in South and Southeast Asia, and northern Australia, causing an estimated 165,000 human cases annually worldwide. Human cases have been reported in the French West Indies (Martinique and Guadeloupe) since the 1990s. Conversely, no human cases have been reported in French Guiana, a French territory in South America. Our study aimed to investigate whether B. pseudomallei is locally established in Guadeloupe and French Guiana. We assessed animal exposure by serology and examined the presence of B. pseudomallei in the environment of seropositive animals. Methodology/Principal findings: Blood samples were collected from domestic animals in two goat farms in Les Saintes, Guadeloupe (n=31), and in 56 farms in French Guiana (n=670) and tested by ELISA. Serological follow up was performed on selected farms. Soil, water and goat rectal swabs were collected and analysed by culture and PCR. In French Guiana, the highest prevalence rates were observed in equids (24%) and cattle (16%), while in Les Saintes, a prevalence of 39% was observed in goats. The longitudinal study in Les Saintes revealed consistent high seropositivity in goats. A B. pseudomallei strain was isolated from the soil from one of the farms and detected in goat rectal swabs from the other farm. Conclusions/Significance: Our environmental investigation prompted by the serologic data confirms the presence of B. pseudomallei in Les Saintes, consistent with documented human cases of melioidosis on this island. In French Guiana, our serologic results call for environmental surveys and a re-evaluation of human infections with melioidosis-like symptoms. The approach developed in this study may help to identify high-risk areas that warrant further investigation.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 80%

Section: Introductionmentioning

confidence: 99%

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Serological screening in animals combined with environmental surveys provides definite proof of the local establishment ofBurkholderia pseudomalleiin Guadeloupe

Gasqué,

Guernier-Cambert,

Manuel

et al. 2024

Preprint

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“…The estimated global incidence of melioidosis is 165,000 cases and 89,000 deaths annually 2-7. The incidence of reported cases is much lower, possibly due to inadequate lab facilities and lack of knowledge about the disease among clinicians 3,6,23…”

Section: Epidemiologymentioning

confidence: 99%

Melioidosis

Borton¹

2022

Nursing

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“…Specificities in critical care comprise the range of infectious diseases, toxicology, envenoming, in addition to a significant rate of cardiovascular diseases and stroke events. Indeed, the diversity of fauna, flora, and ecosystems, as well as the tropical climate with cyclonic components (Guadeloupe and Martinique) and very high rainfall (French Guiana), result in exposure to certain tropical infectious diseases ( Table 2 ) ( 7 , 8 ), which may require specific knowledge and critical care management. In addition, the high level of forestry and aquatic activities, whether professional, military, or recreational, can result in traumatic accidents with specific injuries.…”

Section: Specificities In Critical Carementioning

confidence: 99%

Critical care medicine in the French Territories in the Americas: Current situation and prospects

Kallel

Résière

Houcke

et al. 2021

Revista Panamericana De Salud Pública

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Hospitals in the French Territories in the Americas (FTA) work according to international and French standards. This paper aims to describe different aspects of critical care in the FTA. For this, we reviewed official information about population size and intensive care unit (ICU) bed capacity in the FTA and literature on FTA ICU specificities. Persons living in or visiting the FTA are exposed to specific risks, mainly severe road traffic injuries, envenoming, stab or ballistic wounds, and emergent tropical infectious diseases. These diseases may require specific knowledge and critical care management. However, there are not enough ICU beds in the FTA. Indeed, there are 7.2 ICU beds/100 000 population in Guadeloupe, 7.2 in Martinique, and 4.5 in French Guiana. In addition, seriously ill patients in remote areas regularly have to be transferred, most often by helicopter, resulting in a delay in admission to intensive care. The COVID-19 crisis has shown that the health care system in the FTA is unready to face such an epidemic and that intensive care bed capacity must be increased. In conclusion, the critical care sector in the FTA requires upgrading of infrastructure, human resources, and equipment as well as enhancement of multidisciplinary care. Also needed are promotion of training, research, and regional and international medical and scientific cooperation.

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Three New Cases of Melioidosis, Guadeloupe, French West Indies

Abstract: Mycobacterium tuberculosis by identifying mutations in the 16S rRNA gene. J Clin Microbiol. 1998;36:1220-5. 7. Monot M, Honoré N, Garnier T, Zidane N, Sherafi D, Paniz-Mondolfi A, et al. Comparative genomic and phylogeographic analysis of Mycobacterium leprae.

Cited by 7 publications

References 10 publications

Serological screening in animals combined with environmental surveys provides definite proof of the local establishment ofBurkholderia pseudomalleiin Guadeloupe

Serological screening in animals combined with environmental surveys provides definite proof of the local establishment ofBurkholderia pseudomalleiin Guadeloupe

Melioidosis

Critical care medicine in the French Territories in the Americas: Current situation and prospects

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