In this paper a pointwise sparse domination for generalized Hörmander and also for iterated commutators with those operators is provided generalizing the sparse domination result in [24]. Relying upon that sparse domination a number of quantitative estimates are derived. Some of them are improvements and complementary results to those contained in a series of papers due to M. Lorente, J. M. Martell, C. Pérez, S. Riveros and A. de la Torre [30,29,28]. Also the quantitative endpoint estimates in [24] are extended to iterated commutators. Other results that are obtained in this work are some local exponential decay estimates for generalized Hörmander operators in the spirit of [34] and some negative results concerning Coifman-Fefferman estimates for a certain class of kernels satisfying particular generalized Hörmander conditions.2000 Mathematics Subject Classification. 42B20, 42B25.