Three peroxomorphic H₂O₂ adducts of antibiotic furacin: the first cases of 2D hydrogen-bonded peroxide layers and concerted flip-flop hydrogen disorder of peroxide species

Abstract

Crystallization of antimicrobial compound furacin (nitrofurazone) from 96%, 50%, and 20% hydrogen peroxide (HP) led to three novel solvates C6H6N4O4•H2O2, C6H6N4O4•1.5(H2O2), and C6H6N4O4•3.5(H2O2), respectively. Surprisingly, more rich in hydrogen peroxide...