Three types of swine immunoglobulin-producing tumours: Lymphoplasmacytic lymphosarcoma, immunoblastic lymphosarcoma and plasmacytoma

Kadota, Koichi; Nemoto, Keiichi; Mabara, Susumu; Shirai, Wataru

doi:10.1016/0021-9975(86)90074-5

Cited by 22 publications

(15 citation statements)

References 7 publications

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“…In cases 8-11, the lymphoma tissues located chiefly in the small intestine were composed of cells intermediate between centroblasts and immunoblasts [11,12], and the neoplastic cells were frequently positive for cIgG. Similar cytological features have been reported in ileal lymphomas in young pigs, though not only cIgG-positive but also cIgM-positive cases were detected [23].…”

Section: Discussionsupporting

confidence: 59%

Lymphoid Neoplasms in Swine

Ogihara

Ohba²,

Takai

et al. 2012

J. Vet. Med. Sci.

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ABSTRACT. Seventeen cases of lymphoid neoplasms in swine were investigated and divided into eight histological types. Cases 1-3 were precursor B lymphoblastic leukemias, which occurred in three piglets from the same dam. Cases 4 and 5 were diagnosed, respectively, as a precursor B lymphoblastic lymphoma and a thymic B cell lymphoma, because there were cytological differences between the lymphomas. These five cases of immature B cell malignancies expressed CD79a and terminal deoxynucleotidyl transferase (TdT). Mature B cell lymphomas were divisible into follicular (case 6), diffuse centroblastic (case 7) and intestinal large B cell (cases 8-11) lymphomas. Unlike in case 7, the neoplastic cells in cases 8-11 showed cytological features intermediate between centroblasts and immunoblasts. The mature lymphomas were characterized by positive immunolabeling for CD79a and cytoplasmic immunoglobulins. A case of thymic  T cell lymphoma (case 12) were positive for CD3, CD5, WC1 and TdT. Instead of TdT, perforin was expressed in  T cell lymphomas (cases 13-17), whose histological characteristics were epitheliotropism, homing into T cell zones of lymphatic tissues, and cytological atypia and pleomorphism. In the present study, lymphoid neoplasms could be classified into discrete histological types, some of which were considered to be specific for swine.

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Section: Discussionsupporting

confidence: 59%

Lymphoid Neoplasms in Swine

Ogihara

Ohba²,

Takai

et al. 2012

J. Vet. Med. Sci.

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“…It occurs in several domestic species, such as dogs, cats, cattle, and horses [2,12,13]. However, there have been very few case reports of LPL except those reported in the horse [3] and the pig [4]. We report here a case of cutaneous LPL with systemic involvement in a cat.…”

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confidence: 89%

Cutaneous Lymphoplasmacytic Lymphoma with Systemic Metastasis in a Cat

Kagawa

Yamashita²,

Maetani

et al. 2011

The Journal of Veterinary Medical Science

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ABSTRACT. A lymphoplasmacytic lymphoma was diagnosed in a 12-year-old domestic cat that had a primary cutaneous mass involving the stomach, liver, kidneys, heart, abdominal wall, diaphragm, bone marrow and several lymph nodes. Histopathologically, the most characteristic feature of this tumor was the heterogeneity of cell components, such as small lymphocytes, well-differentiated plasma cells and plasmacytoid transformed lymphocytes. Amyloid was deposited in the skin, stomach, and several lymph nodes. Immunohistochemically, neoplastic small lymphocytes were positive for CD20, and well-differentiated plasma cells and plasmacytoid transformed lymphocytes were positive for -Ig light chains and MUM1/IRF-4. These results emphasize the importance of lymphoplasmacytic lymphoma as a differential diagnosis of extramedullary cutaneous plasmacytoma in cats.KEY WORDS: feline, lymphoplasmacytic lymphoma, skin.

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“…4 Lymphomas affecting the small intestine may be of the alimentary or multicentric form, most of which have been shown to be of B-cell origin. 6,15 In one report of ileal B-cell lymphomas, neoplastic cells originated in Peyer's patches and spread only to regional lymph nodes. 15 A single case of multicentric lymphoma of T-cell origin with involvement of the small intestine has been described.…”

Section: 8mentioning

confidence: 99%

Mucinous Adenocarcinoma and T-Cell Lymphoma in the Small Intestine of 2 Vietnamese Potbellied Pigs (Sus scrofa)

2010

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Small intestinal T-cell lymphoma and mucinous adenocarcinoma are rarely reported in the pig, with most lymphomas being of B-cell origin and only a single report of mucinous adenocarcinoma. Two aged Vietnamese potbellied pigs had concurrent T-cell lymphoma and mucinous adenocarcinoma of the small intestine. The lymphomas formed polypoid masses that projected into the intestinal lumen, whereas the mucinous adenocarcinomas were mural masses that bulged from the serosal surface. Immunohistochemically, neoplastic cells within the lymphomas were positive for CD3 and negative for CD79a. Mucicarmine stain highlighted the abundant cytoplasmic and extracellular mucin in the adenocarcinomas.

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Three types of swine immunoglobulin-producing tumours: Lymphoplasmacytic lymphosarcoma, immunoblastic lymphosarcoma and plasmacytoma

Cited by 22 publications

References 7 publications

Lymphoid Neoplasms in Swine

Lymphoid Neoplasms in Swine

Cutaneous Lymphoplasmacytic Lymphoma with Systemic Metastasis in a Cat

Mucinous Adenocarcinoma and T-Cell Lymphoma in the Small Intestine of 2 Vietnamese Potbellied Pigs (Sus scrofa)

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