Three-year clinical and optical coherence tomography follow-up after stereotactic radiotherapy for neovascular age-related macular degeneration

Persistent and Poor-Responsive Cystoid Macular Edema after Stereotactic Radiotherapy in Neovascular Age-Related Macular Degeneration: A Case Report of Three Patients

“…After radiation therapy involving larger areas than SRT macular edema is a known complication that can often be difficult to treat 10 . Like used in our cases, the first-line treatment is usually intravitreal injection of anti-VEGF drugs, but intravitreal dexamethasone implants are described to be an option for those with poor anti-VEGF response 9 . In our case 3 dexamethasone implant led to an increase in edema compared to anti-VEGF treatment.…”

“…Beside the known types of microvascular abnormalities further vascular changes like polypoidal choroidal vasculopathy 8 and sub foveal choroidal thickness thinning secondary to SRT have been described 9 . This is the first report, describing three cases with additional long-term massive cystoid edema unresponsive to anti-VEGF therapy after SRT.…”