2022
DOI: 10.3389/fpubh.2022.897691
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Threshold effects of body mass index on cognitive function and heterogeneity by sex and cardiovascular risk factors

Abstract: BackgroundDisclosing the underlying relationship between body mass index (BMI) and cognitive decline is imperative for cognitive impairment prevention and early detection. Empirical studies have indicated the risk of abnormal BMI leading to cognitive impairment. However, the relative risk of underweight or overweight on cognitive function is obscure. This study investigated the asymmetric causal effect of BMI on cognitive decline below and above an unknown threshold and the heterogeneity in the threshold level… Show more

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Cited by 5 publications
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“…A study by Tolppanen et al [ 20 ] found that older individuals with higher BMI were less likely to develop dementia than those with lower BMI. Based on previous studies, this difference could be due to the effect of BMI on cognitive performance according to underlying health conditions and non-modifiable factors (such as age and sex) [ 37 , 38 ].…”
Section: Discussionmentioning
confidence: 99%
“…A study by Tolppanen et al [ 20 ] found that older individuals with higher BMI were less likely to develop dementia than those with lower BMI. Based on previous studies, this difference could be due to the effect of BMI on cognitive performance according to underlying health conditions and non-modifiable factors (such as age and sex) [ 37 , 38 ].…”
Section: Discussionmentioning
confidence: 99%