Thrombectomy using the EmboTrap device: core laboratory-assessed results in 201 consecutive patients in a real-world setting

Brouwer, Patrick A.; Yeo, Leonard L.L.; Holmberg, Åke; Andersson, Tommy; Kolloch, Jens; KuntzeSöderqvist, Åsa; Ohlsson, Marcus; Holmin, Staffan; Mpotsaris, Anastasios; Gontu, Vamsi; Bhogal, Paul; Söderman, Michael

doi:10.1136/neurintsurg-2018-013765

Cited by 15 publications

(18 citation statements)

References 38 publications

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“…These recanalization results are slightly higher compared to data from studies with the sole use of Trevo (68.8% TICI ≥ 2b, TRACK registry), a recent core laboratory-audited single-center experience and a previous multicenter series with the sole use of EmboTrap (71.1% and 73% TICI ≥ 2b, respectively). [15][16][17][18] The rate of excellent final reperfusion (mTICI ≥ 2c) by the exclusive use of APH was 71.0% (22/31) in the present study and was comparable to recanalization rate of the AP with 75% (15/20) (mTICI ≥ 2c) and was slightly superior to the recanalization rates of 64.7% mTICI ≥ 2c in the ARISE-II study (64.7%) for EmboTrap. 19 First-pass recanalization rate mTICI ≥ 2b for the solely use of the APH was comparable to the EmboTrap in the recent published ARISE II trial (APH, 58.1% vs. Embo-Trap, 51.5%).…”

Section: Discussionsupporting

confidence: 42%

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A fully radiopaque hybrid stent retriever versus a precursor device: Outcome, efficacy, and safety in large vessel stroke

Weiss

Kabbasch

Lichtenstein

et al. 2022

Journal of Neuroimaging

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Background and Purpose:The aim of this multicenter study was to compare the clinical outcome, safety, and efficacy of the full-length radiopaque Aperio Hybrid stent retriever (APH) with the precursor Aperio thrombectomy device (AP).Methods: Multicentric retrospective analysis of patients with stroke, treated with the APH and AP due to an acute ischemic stroke by large vessel occlusions in the anterior or posterior circulation, was performed. We focused on the comparison of favorable clinical outcome (modified Rankin Scale, 0-2) after 3 months, favorable reperfusion rates (thrombolysis in cerebral infarction scale ≥ 2b), and the complication rate.Results: A total of 51 patients (female: n = 33, 64.7%, mean age 73 ± 16 years) with a median baseline National Institutes of Health Stroke Scale: 15 were treated with the APH or AP. Favorable outcome in patients treated with APH was excellent (44.0%) and comparable to the AP (36.8%). The rate of final favorable reperfusion for both devices was outstanding (APH 31/31 and AP 20/20). The overall complication rate for the APH was slightly higher compared to the AP (32.3%/15.0%). Symptomatic intracranial hemorrhage was recorded in 0 of 51 cases. The all-cause mortality rate at 90 days was 20.0% for the APH and comparable for the AP (21.1%). Conclusions:Comparable clinical outcome, efficacy, and safety of the AP and the recently introduced APH were demonstrated. Both devices appeared feasible, efficient, and safe with regard to endovascular treatment in large vessel occlusion.

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Section: Discussionsupporting

confidence: 42%

“…from other non-RCT stent retriever studies ranging between 15% and 28%. [16][17][18][19] The rate of FO after 3 months (mRS 0-2) was 44.0% (11/25)…”

Section: Correlation With Aphmentioning

confidence: 99%

A fully radiopaque hybrid stent retriever versus a precursor device: Outcome, efficacy, and safety in large vessel stroke

Weiss

Kabbasch

Lichtenstein

et al. 2022

Journal of Neuroimaging

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“…Studies of patients treated with the recent EmboTrap stent-retriever system were not included. Although some data from registries [20][21][22] showed promising results, no comparative data are available on clinical outcomes between the EmboTrap system and Solitaire or Trevo stent retrievers. Studies of patients with anterior circulation occlusion and concomitant cervical carotid occlusion (tandem occlusion) were not excluded.…”

Section: Methodsmentioning

confidence: 99%

First-line contact aspiration vs stent-retriever thrombectomy in acute ischemic stroke patients with large-artery occlusion in the anterior circulation: Systematic review and meta-analysis

et al. 2019

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Background In acute ischemic stroke patients with large-artery occlusion, uncertainties remain about whether clinically important outcomes are comparable between first-line contact aspiration and stent-retriever thrombectomy, although two trials have investigated whether one strategy should be preferred over another. Purpose The purpose of this article is to compare the efficacy and safety of first-line contact aspiration and stent-retriever thrombectomy in stroke patients with anterior circulation large-artery occlusion. Methods We undertook a systematic review of studies of patients treated for large-artery occlusion, with the latest devices of either strategy, within six hours of stroke onset. We determined rates of final complete reperfusion (defined as modified Thrombolysis In Cerebral Infarction score = 3), periprocedural complications and 90-day functional independence (defined as modified Rankin Scale (mRS) score 0–2), and excellent outcome (defined as mRS score 0–1) after contact aspiration and after stent-retriever thrombectomy using random-effects meta-analyses. Any differential effects in rates between the two strategies were assessed using random-effects meta-regressions. Results Fifteen studies (1817 patients) were included. There was no difference in rates of final complete reperfusion at the end of all endovascular procedures between contact aspiration and stent retrievers (51.1%, 95% confidence interval (CI) 39.3–62.9; vs 38.3%, 95% CI 28.6–48.0; pint = 0.14), 90-day functional independence (45.0%, 40.7–49.2; vs 52.4%, 47.7–57.1; pint = 0.45) and excellent outcome (32.1%, 25.7–38.5; vs 34.1%, 21.2–46.9; pint = 0.94). Rates of periprocedural complications did not differ between the two strategies. Conclusions Current data suggest no difference in efficacy and safety between first-line contact aspiration and stent-retriever thrombectomy in stroke patients with large-artery occlusion.

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“…Brouwer et al have published their long experience in mechanical thrombectomy using both EmboTrap and EmboTrap II systems showing slightly better results in terms of successful reperfusion rates (84.6%) but a comparable clinical outcome (52.8%). 23 Anyhow, the use of EmboTrap II seemed technically feasible and safe and the reperfusion rates shown are comparable to that of other devices such as Trevo 21 and Solitaire. 1…”

Section: Discussionmentioning

confidence: 64%

“…have published their long experience in mechanical thrombectomy using both EmboTrap and EmboTrap II systems showing slightly better results in terms of successful reperfusion rates (84.6%) but a comparable clinical outcome (52.8%). 23…”

Section: Discussionmentioning

confidence: 99%

Initial experience with the novel EmboTrap II clot-retrieving device for the treatment of ischaemic stroke

et al. 2019

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Introduction We report our experience with the novel stent-type clot-retrieval device EmboTrap II for the revascularization of large artery occlusions in acute ischaemic stroke. Materials and methods Twenty-nine patients with acute ischaemic stroke due to large artery occlusion underwent mechanical thrombectomy with the new EmboTrap II in two Italian centres. Clinical, procedural and radiological data were collected. Angiographic results and neurological outcomes were analysed. Results Only large vessel occlusions were included. Intravenous thrombolysis was administered in 72% of patients. Successful reperfusion (TICI 2b-3) was obtained in 76% of patients treated exclusively with EmboTrap II. No device-related permanent complications occurred. Conclusion In our experience, mechanical thrombectomy with EmboTrap II is safe and effective. Reperfusion rate was comparable to that obtained with other stent retrievers.

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Thrombectomy using the EmboTrap device: core laboratory-assessed results in 201 consecutive patients in a real-world setting

Abstract: The Embotrap device has a high rate of successful reperfusion. Our core laboratory-audited single-center experience suggests the technical feasibility and safety of the Embotrap for first-line use in a real-world setting.

Cited by 15 publications

References 38 publications

A fully radiopaque hybrid stent retriever versus a precursor device: Outcome, efficacy, and safety in large vessel stroke

A fully radiopaque hybrid stent retriever versus a precursor device: Outcome, efficacy, and safety in large vessel stroke

First-line contact aspiration vs stent-retriever thrombectomy in acute ischemic stroke patients with large-artery occlusion in the anterior circulation: Systematic review and meta-analysis

Initial experience with the novel EmboTrap II clot-retrieving device for the treatment of ischaemic stroke

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