Thrombocytosis

Kessler, Craig M.; Michiels, Jan

doi:10.1016/b978-0-323-46202-0.00019-4

Cited by 3 publications

(1 citation statement)

References 222 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This method of sample collection and handling reduced the reliability of platelet values [ 59 ]. Platelet assessment is a valuable tool in evaluating the response to blood loss [ 60 ]. However, the availability of EDTA tubes and refrigeration of samples were deemed important to ensure the reliability and comparability of other values.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Repeated Blood Harvesting from Pregnant Mares on Haematological Variables

Oddsdóttir,

Jónsdóttir,

Sturludóttir

et al. 2024

Animals

View full text Add to dashboard Cite

Studies have been carried out on the effect of large-volume blood harvesting from horses, but they were performed on nonpregnant horses of various breeds other than Icelandic horses. This study aimed to investigate the effect on the haematological variables indicating erythropoiesis of repeated blood harvesting from pregnant mares. To account for regional variation, two herds of mares were chosen, both kept under free-range conditions. Sequential EDTA blood samples were collected weekly from 160 mares and analysed for haematological variables in an automated analyser. Serum samples from 115 mares were analysed for total protein. In both herds, after three harvests, mares began to measure below the minimum value for erythrocyte numbers, and mild anaemia was present in up to 37% at one time. Mares in only one herd had moderate or marked anaemia, 14.3% of the herd. Both herds showed evidence of increased erythropoiesis, but there was a difference between the herds in the intensity of the response. In both herds, however, all mares had reached the minimum normal haematocrit value three weeks after the last harvest. It is important to investigate the causes for the differences between these herds, which might be addressed to reduce the risk of anaemia.

show abstract

Section: Discussionmentioning

confidence: 99%

The Effect of Repeated Blood Harvesting from Pregnant Mares on Haematological Variables

Oddsdóttir,

Jónsdóttir,

Sturludóttir

et al. 2024

Animals

View full text Add to dashboard Cite

show abstract

Pulmonary hypertension as a risk factor in JAK2-positive polycythemia rubra vera

Nafady

Ahmed

Rashad

et al. 2021

The Egyptian Journal of Haematology

View full text Add to dashboard Cite

Introduction The occurrence of primary pulmonary arterial hypertension (PAH (in primary myeloid proliferation neoplasms seems quite high, up to 22% in polycythemia vera. Polycythemia rubra vera (PRV) is one of the myeloproliferative neoplasms. We aimed to study the incidence of PAH among patients with PRV. Patients and methods A prospective cross-section study was performed on 60 (PRV) patients with PRV confirmed by bone marrow and JAK2 positivity. Abdominal ultrasonography, transthoracic echocardiography, and computed tomography chest were done to estimate the pulmonary hypertension (HTN) and exclude other chest diseases. Results Among the studied 60 patients, we found 14 patients with pulmonary HTN (23.4%) who had significantly increased incidence of comorbidities than patients with normal pulmonary pressure (P=0.009). Moreover, there were statistically significant differences in the size of spleen by ultrasound between the two groups (P=0.008). Patients with pulmonary HTN had a higher hemoglobin level compared with those with normal pulmonary pressure (P=0.006). There was a significant positive correlation between pulmonary pressure and existing comorbidities (diabetes mellitus, HTN, or both) but no correlation with the size of the spleen, hemoglobin level, or white blood cells. Conclusion The prevalence of PAH in JAK2-positive patients with PRV is 76.6%, and there was significant relationship between hematological parameters (hemoglobin, white blood cells, lactate dehydrogenase, and urea level and PAH in JAK2-positive patients with PRV.

show abstract

Mecanismo bioquímico de los cánceres: Una revisión del linfoma

Hernández Centeno,

Sigarán García,

Madrigal Solano

et al. 2023

Rev Fac Med UNIBE

View full text Add to dashboard Cite

Entre los tipos de cáncer que afectan el sistema inmune, está el linfoma caracterizado por ser un conjunto heterogéneo de neoplasias hematológicas de los tejidos linfoides, originando en diferentes progenitores de las células B, células T y células NK. Representan uno de los tipos de cáncer más comunes y poseen una alta tasa de mortalidad. Se clasifica en dos grupos principales, el linfoma de Hodgkin y el linfoma no Hodgkin. Estas células cancerígenas llevan a cabo una reprogramación metabólica aberrante que les permite abastecerse de macromoléculas y metabolitos necesarios para su proliferación, asimismo cuentan con mutaciones en distintas vías de señalización química como aquellas mediadas por citoquinas – JAK/STAT, del factor nuclear kappa-B – y la PI3K/Akt/mTOR, permitiendo regular procesos de la progresión cancerígena. El sistema inmune cuenta con la capacidad de detectar y eliminar células malignas, pero se ha observado que esta enfermedad cuenta con mecanismos y estrategias que permiten erradicar la respuesta inmunitaria y ser resistentes a su regulación mediada por muerte celular y otros procesos moleculares. No obstante, estudios de la biología del cáncer y el desarrollo de novedosos métodos para el diagnóstico y terapia han impactado positivamente en la prevención y control de este tipo de enfermedad.

show abstract

Thrombocytosis

Cited by 3 publications

References 222 publications

The Effect of Repeated Blood Harvesting from Pregnant Mares on Haematological Variables

The Effect of Repeated Blood Harvesting from Pregnant Mares on Haematological Variables

Pulmonary hypertension as a risk factor in JAK2-positive polycythemia rubra vera

Mecanismo bioquímico de los cánceres: Una revisión del linfoma

Contact Info

Product

Resources

About