Thrombocytosis in hospitalized children

Felici, L.; Freddara, Roberta; Pierani, Paolo; Coppa, Giovanni V.; Giorgi, Pier Luigi

doi:10.1016/s0022-3476(05)82683-6

Cited by 1 publication

(4 citation statements)

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“…We and other investigators of pediatric 28 and adult 29 patients cannot explain the association between thrombocytosis and various diseases, such as allergies, metabolic diseases, myopathies, convulsive disorders (without steroid treatment), preoperative stages, and deformities of the skeletal system.…”

Section: Exercisementioning

confidence: 82%

“…A higher incidence of 51% was found by Felici and coworkers. 28 In the study of Heath and Pearson 27 all 15 children with platelet counts of more than 700 X 10 9 /L had infections. The two children with the highest platelet counts (more than 1000 X 10 9 /L) were recovering from pyogenic abscesses, one involving the brain and the other the soft tissue of the arm.…”

Section: Age Distributionmentioning

confidence: 95%

“…When the patients with gastroesophageal reflux are added, the proportion of unexplained thrombocytosis is even one fourth in our study. 1 Felici and coworkers 28 found no explanation for 29% of the cases with thrombocytosis and Gonzenbach and coworkers for 32%. 29 Possible causes for secondary thrombocytosis are summarized in Table 4.…”

Section: Exercisementioning

confidence: 96%

“…Thrombocytosis in childhood is not as rare as was assumed until recently. Newer studies estimate an incidence between 6 and 13% of hospitalized children 12,[25][26][27][28] and of 15% from pediatric outpatients. 27 The variations are due to different definitions of the degree of thrombocytosis.…”

Section: Incidencementioning

confidence: 99%

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Thrombocytosis in Childhood

Sutor¹

1995

Semin Thromb Hemost

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Until recently, thrombocytoses in childhood were considered to be rare. The literature on this subject is scarce and contradictory. When thrombocytosis is defined as a platelet count of more than 500 x 10(9)/L (500 000/mm3 or 500 000/microL), the occurrence in routine examinations at pediatric hospitals can be estimated as 3 to 13%. These are almost exclusively secondary thrombocytoses, which are the result of infections (most frequently), trauma and surgery, hypoxemia, immunologic disturbances, premature birth, gastrointestinal disorders, medications, stress situations, or previous loss of platelets. The secondary thrombocytosis usually has less then 800 x 10(9)/L platelets, is temporary, and occurs predominantly in infants and young children. If only thrombocytosis is present, thrombotic complications are practically nonexistent. Antithrombotic prophylaxis is not necessary unless other risk factors for thrombosis are present, such as vessel damage, permanent iron deficiency, hyperviscosity, immobilization. Primary thrombocytoses due to a defect of stem cells are extremely infrequent in childhood.

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Section: Exercisementioning

confidence: 82%

Section: Age Distributionmentioning

confidence: 95%

Section: Exercisementioning

confidence: 96%