Thrombogenicity of Various Endovascular Stent Types: An In Vitro Evaluation

Tepe, Gunnar; Wendel, Hans Peter; Khorchidi, S; Schmehl, Jörg; Wiskirchen, Jakub; Pusich, Benjamin; Claussen, Claus D.; Duda, Stephan H.

doi:10.1016/s1051-0443(07)61868-5

Cited by 67 publications

(45 citation statements)

References 20 publications

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“…After angioplasty with stenting, the occurrence of in-stent restenosis is one of the major problems. Neointimal growth [1], extracellular matrix proliferation after vessel wall inflammation [2], as well as stent thrombosis [3] are possible reasons for stent restenosis or occlusion. Furthermore mismatch of stent and vessel diameters as well as incorrect deployment of stents are possible reasons for restenosis.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of various image reconstruction parameters in lower extremity stents using multidetector-row CT angiography: initial findings

et al. 2006

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Image quality, visible lumen and patency of lower limb stents was assessed by multidetector-row computed tomography (MDCT) angiography using various reconstruction parameters and the results compared with conventional angiography. Fourteen patients (25 stents) were evaluated. From MDCT datasets, axial and coronal oblique reformations were reconstructed using differing reconstruction parameters (slice thickness, kernel, views). Artifacts and image quality were assessed using a five-degree scale (1=excellent, 5=poor). Visible stent diameter was measured. Stenosis severity was compared with calibrated catheter angiography. The image quality of medium and sharp image kernels were good/fair (1.9-2.4), while smooth kernel provided only acceptable/poor image quality (3.9-4.4). Coronal oblique images were rated superior to assess in-stent lumen rather than axial. Using medium and sharp kernels, the visible stent lumen was significantly greater than using smooth kernel (P<0.001). thirteen out of fourteen patients (24/25 stents) were correctly classified as patent. In one patient, in-stent stenosis (> or =50%) was falsely diagnosed using CT angiography (CTA) with smooth kernel and was, therefore, rated as false positive. Coronal oblique views, as well as medium and sharp kernels, have shown the best results regarding image quality to assess stent patency in the lower limb. Therefore, MDCT could be a valuable non-invasive modality for stent imaging in the peripheral vasculature.

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Section: Introductionmentioning

confidence: 99%

Evaluation of various image reconstruction parameters in lower extremity stents using multidetector-row CT angiography: initial findings

et al. 2006

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“…Recent findings suggest that coatings with radioactive marked substances [21], cytostatics or immunosuppressants [22], or heparin [23] for endocoronary prostheses may increase graft patency [24]. Nevertheless we are not able so far to reduce completely cell activation and thrombogenicity of even coated devices and first studies appear being in doubt with, e.g.…”

Section: Discussionmentioning

confidence: 96%

Thrombospondin 1 as possible key factor in the hemocompatibility of endocoronary prostheses

et al. 2005

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“…Nitinol is also known to be resistant to thrombus formation and does not calcify (1)(2)(3)(4)(5)(6)(7)(8)(9). A thin titanium oxide layer forms on nitinol's surface, similar to that formed on Ti, and prevents corrosion or reaction of the bulk material in physiologic solutions.…”

Section: Shape Memory Alloysmentioning

confidence: 99%

Smart Materials Applications for Pediatric Cardiovascular Devices

2008

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"Smart Materials" are materials that change their shape, color, or size in response to an externally applied stimulus. While smart materials have already made a tremendous impact on our lives through their applications in liquid crystal displays, headphones, fuel injection systems, flexible cell phone antennas, and many other commercial products, they also have the potential to help many pediatric patients. This review focuses on with the present and potential applications of shape memory alloys, piezoelectric materials, and the relatively newer class of materials called magnetostrictive and ferromagnetic shape memory alloys in the design of pediatric cardiovascular devices. (Pediatr Res 63: 552-558, 2008) "S mart Materials" are materials that change their shape, color, or size in response to an externally applied stimulus. Examples of "external stimuli" include changes in temperature, application of an electric or magnetic field, and changes in moisture or pH. Thus, whereas other materials play passive structural roles in devices, smart materials can actually be manipulated in situ.During the last few decades smart materials have had a tremendous impact on a variety of fields. For example, chromogenic materials are the basis of all liquid crystal displays and photochromes allow eyeglasses to change to sunglasses in the presence of sun light. The basis of lighter igniter switches, headphones, and recent fuel injection systems is piezoelectrics whereas the flexible cell phone antennas and eyeglasses are shape memory smart materials. Many more commercial applications for smart materials are already available and new ones are being studied by a wide range of organizations.This review focuses on with the potential applications of shape memory alloys, piezoelectric materials, and the relatively newer class of materials called magnetostrictive and ferromagnetic shape memory alloys (FSMA) in the design of pediatric cardiovascular devices. Whereas shape memory alloys like nitinol (a nickel-titanium alloy) change shape in response to a change in temperature, magnetostrictive or ferromagnetic materials change their shape in response to a magnetic field. NiMnGa (nickel-manganese-gallium) and Terfenol-D represent the best known examples of FSMA and magnetostrictive materials respectively. The more mature class of piezoelectric materials, e.g., BaTiO 3 and lead zirconate titanate (Pb(ZrTi)O 3 )-commonly called PZT, change shape with an electrical field; or, conversely, generate an electrical signal in response to a forced change in shape. All of these materials can be used as either an actuator or a sensor.Smart materials have begun to have a significant impact in the field of medicine. Although a number of applications already exist, it is only a matter of time before many more pediatric applications will emerge for these smart materials. SHAPE MEMORY ALLOYSNitinol introduction. NiTi or nitinol is a nickel-titanium shape memory alloy. Nitinol is a pneumonic for NickelTitanium, developed by the Naval Ordinance Labo...

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Thrombogenicity of Various Endovascular Stent Types: An In Vitro Evaluation

Cited by 67 publications

References 20 publications

Evaluation of various image reconstruction parameters in lower extremity stents using multidetector-row CT angiography: initial findings

Evaluation of various image reconstruction parameters in lower extremity stents using multidetector-row CT angiography: initial findings

Thrombospondin 1 as possible key factor in the hemocompatibility of endocoronary prostheses

Smart Materials Applications for Pediatric Cardiovascular Devices

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