The paper gives an overview of recent investigations dealing with the problem of venous thromboembolic events (VTEEs) in cancer surgery. Particular emphasis is placed on the data related to a search for the most informative laboratory indicators that may serve as predictors for VTEEs. Thrombodynamics assay, a new promising laboratory technique, is also described. Investigations have shown its effectiveness and ease in data interpretation when evaluating the hemostatic system and especially in hypercoagulable states.