“…Isolated reports have proposed bedside administration of local thrombolytic therapy in high-risk PE patients via a transjugular Swan-Ganz pulmonary artery catheter. 4,5 A review of literature on local administration of thrombolytic drugs in patients with acute PE was conducted using the PubMed database. Relevant case reports in English were identified using a combined text word and Medical Subject Headings (MeSH) search strategy with the following combination of keywords: Swan-Ganz thrombolysis and PE, Thrombolytic therapy in PE and Swan-Ganz, and Swan-Ganz and PE.…”