Thrombosis and risk factors

Akar, Nejat

doi:10.5152/tjh.2010.58

Cited by 5 publications

(3 citation statements)

References 10 publications

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“…In the monitoring of patients who had perinatal stroke, epilepsy, motor function, language, and cognition disorders may be observed in the long term. 5 , 6 , 10 – 17 Cerebral palsy is the most frequently encountered motor function disorder. 17 , 18 Our study found a cerebral palsy prevalence in children with neonatal stroke over the age of 3 of 42.8%) ( Table 4 ).…”

Section: Discussionmentioning

confidence: 99%

“…The genotypes of FV G1691A, PT G20210A, and MTHFR C677T were determined via polymerase chain reaction and restriction fragment analysis, as previously reported. 14 The study protocol was approved by the Ankara University Ethics Committee, and written informed consent was obtained from the parents of each patient prior to performing any procedures.…”

Section: Methodsmentioning

confidence: 99%

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Investigating the Impact on Long-Term Outcomes and the Necessity of Hereditary Thrombophilia Screening in Presumed or Perinatal Arterial Ischemic Stroke

Bektaş,

Göktaş,

Atasay

et al. 2024

Clin Appl Thromb Hemost

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This study aimed to investigate the influence of prothrombotic risk factors on long-term outcomes of patients with perinatal arterial ischemic stroke. The study was conducted through an analysis of monitoring results that were regularly maintained for approximately 20 years at a tertiary stroke-monitoring center. The study assessed prothrombotic risk factors, radiological area of involvement, clinical presentation, treatments, clinical outcomes, and long-term outcomes of the 48 patients included in the study, with a mean monitoring time of 77.6 ± 45.7 months (range: 6-204). Our results showed that the presence of prothrombotic risk factors did not affect long-term outcomes. However, patients with middle cerebral artery infarction had the highest risk of developing cerebral palsy, whereas those with presumed stroke had the highest risk of developing epilepsy. This study suggests that prothrombotic risk factors should not be evaluated during the acute stage unless there is a strong suspicion of the patient's history, and prevention or early diagnosis of presumed stroke patients will positively impact their long-term prognosis.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Investigating the Impact on Long-Term Outcomes and the Necessity of Hereditary Thrombophilia Screening in Presumed or Perinatal Arterial Ischemic Stroke

Bektaş,

Göktaş,

Atasay

et al. 2024

Clin Appl Thromb Hemost

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“…We read with great interest the recent publication byAkar related to thrombosis and risk factors, in which hereached in conclusion that in case of need only homocysteine(Hcy) levels should be routinely analyzed and notthe 5, 10-methylenetetrahydrofolate reductase (MTHFR)677 T polymorphism [ 1 ]. The methylation of Hcy tomethionine is catalyzed by the MTHFR enzyme.…”

Section: To the Editormentioning

confidence: 99%