Abstract-The physiological parameters monitoring of human target are considered to be a meaningful and challenging task in non-lineof-sight (NLOS) scenes such as rescue of trapped survivors in postdisaster. In this paper, a new method based on developed adaptive line enhancer (DALE) is proposed to monitor vital signs via ultra-wideband (UWB) radar with centre frequency of 400 MHz. The validity of this new method is proved by means of two experiments with different positions of human target. The good results demonstrate that this new method can be used for vital sign monitoring including respiration and heartbeat through the obstacle. Furthermore, the motion responses due to respiration and heartbeat in different body positions are also discussed.