THU0048 Addition of the rgd motif in the fibre knob of an adenoviral vector improved the transfection efficiency and when used for overexpression of il-1ra resulted in a more effective inhibition of arthritis

Abstract

THU0046Table 1 sE-selectin (ng/ml) sL-selectin (ng/ml) sP-selectin (ng/ml) RA 43.7 ± 30.9 a 378 ± 168 b, c 383 ± 198 c SSc 44.9 ± 22.3 d 552 ± 224 246 ± 163 Healthy subjects 24.9 ± 12.9 672 ± 140 292 ± 199 a p <0.05 vs. healthy subjects; b p <0.001 vs. healthy subjects; c p <0.01 vs. SSc; d p <0.01 vs healthy subjects.