THU0106 The expression of ip-10 and mig chemokines in rheumatoid synovial tissue

Abstract

Background Parvovirus B19 may cause an acute or chronic polyarthropathy, which in many cases fulfils the criteria of the American College of Rheumatology for the diagnosis of rheumatoid arthritis (RA). Additionally, parvovirus B19 has been implicated in the pathogenesis of RA. Objectives The aim was to investigate the presence of antibodies to parvovirus B19 in patients with RA and osteoarthritis (OA). Methods In the study were included 50 patients with RA, 24 patients with OA and 26 healthy controls. In all patients IgG and IgM antibodies to parvovirus B19 were measured by indirect immunofluorescence.