THU0478 Determination of comorbidities in fibromyalgia syndrome

Abstract

BackgroundAlthough fibromyalgia syndrome is diagnosed by excluding other possible diagnosis based on the patient's clinical features, in recent the studies, it was shown that comorbid diseases affect the course of fibromyalgia.ObjectivesThe aim of this study is to evaluate the comorbid diseases of patients with fibromyalgia and to determine the rates of comorbid diseasesMethodsIn this study, age, gender and comorbid diseases of patients above 18 years and diagnosed with fibromyalgia by a were evaluated in the database system of the hospital retrospectively.ResultsA total of 509 patients were examined in our study. 51 of the patients were male, 458 were female (mean age was 50.24±12.32). Of the patients, 345 (67.8%) had at least one comorbid disease while 164 (32.2%) had no comorbid disease. In the study, 187 of the patients (36.7%) had cardiovascular diseases, 157 of the patients (30.8%) had endocrine diseases, 63 of the patients (12.4%) had rheumatologic diseases, 30 of the patients (5.9%) had neurological diseases, 14 of the patients (2.8%) had other autoimmune diseases, 10 of the patients (2.0%) had cancers, 129 of the patients (25.3%) had mental disorders, 45 of the patients (8.8%) had chronic lung diseases, 37 of the patients (7.3%) had osteoporosis, 11 of the patients (2.2%) had other diseases (chronic pancreatitis, chronic renal failure, nephrotic syndrome, deep vein thrombosis, hepatitis serology positivity, pulmonary thromboembolism, organ transplantation).ConclusionsFMS is an important disease that is increasing in frequency in recent years. FMS, which can be seen with many diseases, is in fact related to physicians from many branches, and it is useful to evaluate FMS patients with their comorbid conditions on their follow-up.References Choy EH & Mease PJ. Key symptom domains to be assessed in fibromyalgia (outcome measures in rheumatoid arthritis clinical trials). Rheumatic Disease Clinics of North America, 2009; 35(2):329–337.Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Arthritis & Rheumatism, 1990; 33(2):160–172.Soran N, Altındağ Ö, Demirkol A, Sallı A, Yılmaz H, Kocabaş H, et al. Depression level and relation with clinical parameters in fibromyalgia syndrome. Rheumatism, 2008; 23:1–4. Disclosure of InterestNone declared

Possible relations between arterial hypertension and cervical spine fibromyalgias (literature review)

“…Clinical studies have shown the presence of widespread cerebral blood flow dysfunction in hypertension, especially in patients not receiving any antihypertensive treatment or with inadequate antihypertensive therapy applied (Ripp and Rebrova, 2021). On the other hand, analysis of 509 patients with FM revealed that 187 of them (36.7%) were diagnosed with cardiovascular disease (Bilge et al, 2017); in a different study in 941 patients aged 18-87 years (with an established FM diagnosis) circulatory disorders were revealed and observed in the surveyed age groups as follows: 18-29 years old -28 people (3%), 30-39 years old -39 people (4.2%), 40-49 years old -92 people 9.8%), 50-59 years old -101 people (10.8%), 60-69 years old -33 people (3.5%), 70-87 years old -6 people (0.6%), which indicates predominance of such disorders in adults suffering from FM (Häuser et al, 2019). Chronic headache in FM has also been reported (Kleykamp et al, 2021), with suggestions that FM may be a manifestation of idiopathic intracranial hypertension (Altaraqji et al, 2021).…”

Patient-Reported Outcomes Following Inpatient Multimodal Treatment Approach in Chronic Pain-Related Rheumatic Diseases

“…Rheumatic diseases are often associated with a large number of comorbidities, 39 , 40 which are not always treated alongside the main disease. 41 These comorbidities may vary widely and include gastrointestinal problems, headaches, cardiovascular diseases, depression, or other diseases of the musculoskeletal system, and so on.…”

Frequency of Vitamin D Deficiency in Patients Presenting With Fibromyalgia

“…Endocrinopathies, rheumatologic diseases, kidney diseases and mental health problems are some of the diseases linked with vitamin D deficiency among the individuals. 7,8 Vitamin D deficiency among the patients suffering from both fibromyalgia and other rheumatologic diseases has been frequently documented in the scientific literature. Makrrani et al concluded that vitamin D deficiency was more prevalent in fibromyalgia patients as compared to the controls.…”