Thymic basaloid carcinoma with hepatic metastasis

Fine‐needle aspiration cytology of thymic basaloid carcinoma: Case studies and review of the literature

“…7 The male-to-female ratio is 8:5. 8 An associated thymic cyst is present in 11 of 14 cases, including two of our current cases. 3,[6][7][8][9][10][11] BTCs have metastatic potential and metastases to the lung and the liver have been previously reported.…”

“…Although most cases of BTCs reported in the surgical pathology literature did not show immunoreactivity for neuroendocrine markers, there have only been three cases for which this has been immunostained in the 80s and 90s. [6][7][8] Although all of our cases of BTCs showed some degree of neuroendocrine differentiation, there was only focal and variable but real neuroendocrine differentiation as evidenced by finding membrane bound neurosecreDiagnostic Cytopathology DOI 10.1002/dc tory granules in areas of the tumor by electron microscopy. And although the differential diagnosis then becomes that of a large-cell neuroendocrine carcinoma, these tumors are clinically highly aggressive and usually show diffuse and strong immunoreactivity for any one of these markers of neuroendocrine differentiation.…”

“…3,[6][7][8][9][10][11] BTCs have metastatic potential and metastases to the lung and the liver have been previously reported. 3,4,8 FNABs were performed in three of those cases. Of these, the biopsy samples were insufficient for diagnosis in two cases; the diagnosis was inconclusive in the third.…”

“…Of these, the biopsy samples were insufficient for diagnosis in two cases; the diagnosis was inconclusive in the third. [6][7][8] One case of BTC is unusual because of the presence of PAS-positive goblet cells arranged in glands; this finding is interpreted as goblet-cell metaplasia by the researchers. 5 FNAB is an important tool in the diagnosis of mediastinal masses.…”

Thymic basaloid carcinoma with pleural dissemination that developed after a curative resection: Report of a case

“…2-6,10,11 Alternatively, case reports from Japan, 7-9,12-19 although most of them were written in Japanese, [12][13][14][15][16][17][18][19] described the treatment, surgical procedure, recurrence, and prognosis in detail. [7][8][9]13,[15][16][17][18][19] Table 1 shows the median age of the patients to be 59 years (range, 34-77 years); there was a predominance of male patients (24/35, 69%), the average tumor size (including concomitant cyst) was 8.4 cm (range, 2.8-20 cm), most surgical interventions were accompanied by a combined resection of adjacent structures, and 10 out of 27 patients (37%), whose prognoses were recognized, died. No death from the tumor was reported in the English literature until 2006, and the prognosis of the patients with thymic basaloid carcinoma was generally considered to be favorable.…”