2014
DOI: 10.1016/j.jaci.2014.04.022
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Thymic stromal lymphopoietin links keratinocytes and dendritic cell–derived IL-23 in patients with psoriasis

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Cited by 84 publications
(95 citation statements)
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“…patients with psoriasis decreased DC activation [15]. The present study suggests that a TSLP blockade could also have therapeutic potential for patients with RA.…”
Section: Discussionsupporting
confidence: 58%
“…patients with psoriasis decreased DC activation [15]. The present study suggests that a TSLP blockade could also have therapeutic potential for patients with RA.…”
Section: Discussionsupporting
confidence: 58%
“…First, we measured TSLP levels in those supernatants, even if dissociation between in situ expression and secretion in tissue-derived supernatants was previously observed. 5 We could not detect significant TSLP levels within the majority of the tested tumorderived supernatants (Fig. S1A).…”
Section: Blood Cd11cmentioning
confidence: 85%
“…The specificity of the anti-TSLP mAb staining was previously validated on human skin and tonsillar sections. 5 Normal and atopic dermatitis skin sections were used for TSLP expression as negative and positive controls, respectively. 2 As expected, TSLP was found to be highly expressed in keratinocytes of skin lesions obtained from atopic dermatitis patients (Fig.…”
Section: Tslp Is Overexpressed In Highly Differentiated Hnscc Tumorsmentioning
confidence: 99%
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“…When LPS receptors or CD14 on these cells are activated, inflammation is triggered by the NF-κB pathway. As results of LPS induction, the activated immune cells immediately secrete TNF-α as well as other pro-inflammatory cytokine which probably lead to IL17, IL24, and IL33 production from keratinocytes (Balato et al, 2012;Chiricozzi et al, 2011;Kumari et al, 2013;Volpe et al, 2014). Furthermore, mutations in loci coding the transcriptional factors may initiate lesions.…”
Section: Introductionmentioning
confidence: 99%