Thymol derivatives with antibacterial and cytotoxic activity from the aerial parts ofAgeratina adenophora

Abstract

Eight thymol derivatives including three new ones (1–3) were obtained from the aerial parts of Ageratina adenophora, with most of them, in particular 1 and 5, showing notable in vitro antimicrobial and cytotoxic activity.

Biological properties of active compounds from Ageratina adenophora

“… 19 The thymol derivatives of A. adenophora have also exhibited inhibitory effects on both gram-negative and gram-positive bacteria. 20 Furthermore, bioactive quinic acid derivatives from A. adenophora have in vitro antibacterial activity toward five assayed bacterial strains. 21 …”