Thymoma-Associated Autoimmune Enteropathy: A Report of Two Cases

Mais, Daniel D.; Mulhall, Brian P.; Adolphson, Kimberly R.; Yamamoto, Kazuhisa

doi:10.1093/ajcp/112.6.810

Cited by 49 publications

(24 citation statements)

References 6 publications

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“…We describe an adult patient with a history of thymoma who was diagnosed with AIE, the third reported adult patient with AIE who also had this tumor (11). The comorbidity of these conditions is consistent with the proposed disease pathogenesis.…”

Section: Discussionsupporting

confidence: 75%

“…Recently, Mais et al reported two cases of possible AIE in association with thymoma. Only one of the cases displayed antienterocyte antibodies, but both had other features consistent with AIE (11). Several cases of unclassified chronic diarrhea in association with thymoma (the majority having hypogammaglobulinemia) also have been described; most had villous atrophy as well as colonic lesions resembling graft-versus-host disease (GVHD) (12)(13)(14)(15)(16).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Adult-Onset Autoimmune Enteropathy in the Setting of Thymoma Successfully Treated with Infliximab

Elwing

Clouse

2005

Dig Dis Sci

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Section: Discussionsupporting

confidence: 75%

mentioning

confidence: 99%

Adult-Onset Autoimmune Enteropathy in the Setting of Thymoma Successfully Treated with Infliximab

Elwing

Clouse

2005

Dig Dis Sci

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“…The association between AIE and thymoma has been described in both pediatric and adult patients and provides further evidence about the role of thymoma and the development of autoimmunity [24,25].…”

Section: Introductionmentioning

confidence: 70%

The Spectrum of Autoimmune Enteropathy

Nedelkopoulou

Farmaki

Deheragoda

et al. 2015

Textbook of Pediatric Gastroenterology, Hepatology and Nutrition

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“…A number of reports in adults [1][2][3][4][5][6][7] , similar to prior publications in children [8][9][10] , have described an entity, termed autoimmune enteropathy (AIE), that appears to involve mainly, but not exclusively, the small intestine [4,7] .…”

Section: Components Of Diagnosismentioning

confidence: 96%

Adult autoimmune enteropathy

Freeman¹

2008

WJG

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Recent reports have suggested that autoimmune enteropathy involving the small bowel may occur in adults as well as in children. Apparently, the endoscopic and histological changes are similar to celiac disease before treatment, but these are not altered by any form of dietary restriction, including a gluten-free diet. As in celiac disease, histologic changes in gastric and colonic biopsies have also been recorded. Antienterocyte antibodies detected with immunofluorescent methods have been reported by a few laboratories, but these antibodies appear not to be specific and may simply represent epiphenomena. A widely available, reproducible and quantitative anti-enterocyte antibody assay is needed that could be applied in small bowel disorders that have the histological appearance of celiac disease, but fail to respond to a gluten-free diet. © 2008 WJG . All rights reserved.Key words: Celiac disease; Autoimmune enteropathy; Anti-enterocyte antibodies; Anti-goblet cell antibodies; Antibodies in celiac disease Peer reviewer: Hitoshi Asakura, Director, Emeritus Professor, International Medical Information Center, Shinanomachi Renga Bldg.35, Shinanomachi, Shinjukuku, Tokyo 160-0016, Japan F r e e m a n H J . A d u l t a u t o i m m u n e e n t e r o p a t h y.

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Thymoma-Associated Autoimmune Enteropathy: A Report of Two Cases

Cited by 49 publications

References 6 publications

Adult-Onset Autoimmune Enteropathy in the Setting of Thymoma Successfully Treated with Infliximab

Adult-Onset Autoimmune Enteropathy in the Setting of Thymoma Successfully Treated with Infliximab

The Spectrum of Autoimmune Enteropathy

Adult autoimmune enteropathy

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