Thyroid carcinoma in intrathoracic goiter

Nervi, M; Iacconi, Pietro; Spinelli, Claudio; Jannì, A; Miccoli, Paolo

doi:10.1007/s004230050144

Cited by 31 publications

(21 citation statements)

References 9 publications

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“…One of the most common symptoms of compression from retrosternal goitres is dyspnea. Both our patients presented with these symptoms and given the slow growth of the mass and typical age of these patients these symptoms are often mistaken for diagnoses such as chronic obstructive pulmonary disease or cardiac failure [3]. The presence of dyspnea and history of prior thyroid resection, as in case two, should alert the physician of a recurrent goitre.…”

Section: Discussionmentioning

confidence: 80%

Acute Presentation of Massive Retrosternal Thyrotoxic Goitres*

Lodhia¹,

Christensen²,

Bishay³

et al. 2013

OJTS

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Approximately 5% of goitres extend below the thoracic inlet and can potentially become life threatening due to compression of the airway and major vessels. Approximately 7% of these goitres which require surgical resection will need an additional sternotomy to deliver the intra-thoracic component. Massive retrosternal toxic goitres presenting acutely are rare and are described infrequently in literature. We hereby present two cases of massive retrosternal thyrotoxic goitres presenting with acute respiratory failure, requiring non-invasive ventilation, as well as significant head and neck venous compression. Surgery on the thyrotoxic patient with a goitre, even if not significantly enlarged, is associated with a high peri-operative mortality due to cardiac instability and hemorrhage. We discuss the challenges of surgical intervention in these patients with particular emphasis on the timing of surgery to relieve compressive symptoms and the time needed to achieve a euthyroid state. We also emphasize the need for meticulous hemostasis, use of a cell-saver, transfusion protocols, adjuncts to hemostasis, as well as careful monitoring and continuous adjustments to the coagulation profile.

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Section: Discussionmentioning

confidence: 80%

Acute Presentation of Massive Retrosternal Thyrotoxic Goitres*

Lodhia¹,

Christensen²,

Bishay³

et al. 2013

OJTS

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“…The majority of cervical and retrosternal goiters are extensions and enlargement of thyroid gland. However, in some studies the prevalence of thyroid cancer has been reported up to 23% in retrosternal goiter (5).…”

Section: Discussionmentioning

confidence: 99%

Ten-year Comparison of the Prevalence of Thyroid Cancer in the Neck With Retrosternal Thyroid in Shahid Beheshti and Ayatollah Rouhani Hospitals in Babol, Iran

et al. 2015

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Background: Any deviation in the normal descent of the thyroid gland can lead to ectopic thyroid. In this study ten-year comparison of the prevalence of cervical thyroid cancer with retrosternal thyroid was performed. Objectives: By knowing prevalence of the disease actions may be performed to know the risk factors associated with the disease. The purpose of this study was to compare the prevalence of cervical thyroid cancer with retrosternal thyroid in Shahid Beheshti and Ayatollah Rouhani Hospitals in Babol, Iran, during 2000 -2010. Materials and Methods: This cross-sectional study was performed on 158 patients referred to Shahid Beheshti and Ayatollah Rouhani Hospitals in Babol City, Iran, during 10 years (from 2000 -2010). Demographic characteristics, smoking, family history of thyroid cancer, the signs and symptoms and pathology reports were collected in a checklist format. Results: From a total of 158 patients with thyroid cancer, 144 cases were diagnosed with cervical thyroid and 14 cases diagnosed with retrosternal thyroid. In both groups, dyspnea and hoarseness were the most prevalent symptoms. The pathology report showed that in the cervical thyroid, benign cases were more than malignant cases but in retrosternal thyroid, the opposite happened. Conclusions: The prevalence of cervical thyroid was 91.1% and the prevalence of retrosternal thyroid was about 8.9%. The prevalence rates of malignancy in the cervical and retrosternal thyroid were 34.7% and 21.4%, respectively.

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“…Focal or diffuse uptake of thyroid can be seen in various benign and malignant conditions, including thyroid carcinoma, metastatic tumor, thyroiditis, multinodular goiter and nodular hyperplasia [15]. Acute suppurative thyroiditis may occur in intrathoracic ectopic thyroid [16] and cancer can occur in 3% to 10% of intrathoracic ectopic thyroid [2,17]. Although there is no consensus for the optimal therapeutic strategy, surgical treatment can be considered based on some parameters, such as size, local symptoms, and complication of the mass (ulceration, bleeding, cystic degeneration, malignant transformation) [6,18].…”

Section: Discussionmentioning

confidence: 99%

A Case of Right Paratracheal Ectopic Thyroid, Mimicking Metastasis on CT and 18F-FDG PET CT

Kim¹

2013

OJMI

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Mediastinal ectopic thyroid is quite rare, occurring in less than 1% of all ectopic thyroids. Frequent location of mediastinal ectopic thyroid in reported cases is anterosuperior mediastinum. CT findings of ectopic thyroid can be various and are dependent on several factors, such as its iodine content, the extent of tissue degeneration, and the presence of colloid cysts. This is a case of right paratracheal ectopic thyroid with nodular hyperplasia, mimicking metastatic nodal mass on both CT and 18 F-FDG PET CT in a patient with colon cancer.

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Thyroid carcinoma in intrathoracic goiter

Cited by 31 publications

References 9 publications

Acute Presentation of Massive Retrosternal Thyrotoxic Goitres*

Acute Presentation of Massive Retrosternal Thyrotoxic Goitres*

Ten-year Comparison of the Prevalence of Thyroid Cancer in the Neck With Retrosternal Thyroid in Shahid Beheshti and Ayatollah Rouhani Hospitals in Babol, Iran

A Case of Right Paratracheal Ectopic Thyroid, Mimicking Metastasis on CT and 18F-FDG PET CT

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